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Showing 1–3 of 3 results
Advanced filters: Author: Thomas Delerue Clear advanced filters

  • Frailty is associated with an increased risk for negative health outcomes in older populations, and being able to predict frailty could facilitate prevention measures. By performing an epigenome-wide screen, the authors derived a DNA methylation based measure for frailty which can predict both prevalence and longer-term incidence of frailty.

    • Xiangwei Li
    • Thomas Delerue
    • Hermann Brenner
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-11

  • Reproducibility is key to all fields of research, and in the case of animal research, this can be hampered by inconsistent reporting of animal genetics. Here the authors propose a reporting framework and guidelines designed to discuss the validation and standardise the reporting of genetic backgrounds and genetic alterations in animal models.

    • Lydia Teboul
    • James Amos-Landgraf
    • Guillaume Pavlovic
    ReviewsOpen Access
    Nature Communications
    Volume: 15, P: 1-8