Advanced search

Filter By:

Journal Check one or more journals to show results from those journals only.

Choose more journals

Article type Check one or more article types to show results from those article types only.
Subject Check one or more subjects to show results from those subjects only.
Date Choose a date option to show results from those dates only.

Custom date range

Clear all filters
Sort by:
Showing 1–8 of 8 results
Advanced filters: Author: Thomas E. Ouldridge Clear advanced filters

  • Programmable self-assembly can help construct complex nanostructures. Now a mathematical framework can identify if and how a particular structure can be assembled.

    • Maximilian C. Hübl
    • Thomas E. Videbæk
    • Carl P. Goodrich
    ResearchOpen Access
    Nature Physics
    P: 1-8

  • In a non-equilibrium environment, molecular machines can undergo a directed flow through configurational changes, a feature that is widely exploited in processes characteristic of life. The use of such a flow to enhance the specificity of molecular recognition beyond equilibrium conditions has now been demonstrated in a minimal, synthetic, DNA-based system.

    • Thomas E. Ouldridge
    • Rakesh Mukherjee
    News & Views
    Nature Nanotechnology
    Volume: 20, P: 1359-1360

  • Information-bearing templates that catalyse the assembly of complex macromolecules are a central motif of natural biochemistry, but their power remains largely unexplored in synthetic contexts. Enzyme-free templating of DNA dimerization has now been demonstrated, using DNA nanotechnology to ensure that the templates are effective information-propagating catalysts.

    • Javier Cabello-Garcia
    • Rakesh Mukherjee
    • Thomas E. Ouldridge
    ResearchOpen Access
    Nature Chemistry
    Volume: 17, P: 1179-1187

  • The self-assembly process of DNA nanostructures is still not well understood, especially for DNA origami. Here, the authors present a mesoscopic model that uses a switchable force field to capture the mechanical behavior of single- and double-stranded DNA motifs and transition between them, allowing access to the long assembly timescales of DNA origami up to several kilobases in size.

    • Marcello DeLuca
    • Daniel Duke
    • Gaurav Arya
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-13

  • Synthetic molecular systems require subtle control over their thermodynamics and reaction kinetics to implement features such as catalysis. Here the authors propose using mismatches in a DNA duplex to drive catalytic reactions forward whilst maintaining tight catalytic control.

    • Natalie E. C. Haley
    • Thomas E. Ouldridge
    • Andrew J. Turberfield
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-11

  • The operation of DNA-based molecular devices often relies on toehold-mediated strand displacement. Here, the authors show how mismatches in base pairing can be used for the kinetic control of strand displacement, tuning the rate constant over three orders of magnitude.

    • Robert R. F. Machinek
    • Thomas E. Ouldridge
    • Andrew J. Turberfield
    Research
    Nature Communications
    Volume: 5, P: 1-9

  • Probing the assembly process that occurs when single-stranded DNA is folded into desired shapes by ‘DNA origami’ shows that it can be guided by controlling the strengths of local and long-range interactions, enabling more reproducible synthesis.

    • Katherine E. Dunn
    • Frits Dannenberg
    • Jonathan Bath
    Research
    Nature
    Volume: 525, P: 82-86