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Blood–brain barrier permeability of adipokines and myokines

The use of adipokines and myokines measured in serum or cerebrospinal fluid as biomarkers or disease modifiers in neurological disorders is limited. Their permeability to the blood–brain barrier is either unknown or overlooked. A novel classification of adipokines and myokines on the basis of their cerebrospinal fluid to serum ratio is warranted.

Andreas Schäffler
Andreas Schmid
Thomas Karrasch
Comments & Opinion03 Feb 2026
Nature Reviews Endocrinology

Volume: 22, P: 257-258
Projection map of aquaporin-1 determined by electron crystallography

Using cryo-electron microscopy we have determined a projection map of the structure of the water-selective pore aquaporin-1.

Thomas Walz
Dieter Typke
Andreas Engel
Correspondence01 Sept 1995
Nature Structural Biology

Volume: 2, P: 730-732
Dynamics of the human bile acid metabolome during weight loss

Andreas Schmid
Gerhard Liebisch
Andreas Schäffler
ResearchOpen Access28 Oct 2024
Scientific Reports

Volume: 14, P: 1-11
Fostering the exchange of real world data across different countries to answer primary care research questions: an UNLOCK study from the IPCRG

Liza Cragg
Siân Williams
Niels H. Chavannes
ResearchOpen Access08 Mar 2018
npj Primary Care Respiratory Medicine

Volume: 28, P: 1-9
Genome-wide association analysis identifies six new loci associated with forced vital capacity

Stephanie London, Martin Tobin and colleagues report meta-analyses of genome-wide association studies for forced vital capacity (FVC), a spirometric measure of pulmonary function that reflects lung volume. They identify six regions newly associated with FVC and demonstrate that candidate genes at these loci are expressed in lung tissue and primary lung cells.

Daan W Loth
María Soler Artigas
Stephanie J London
Research15 Jun 2014
Nature Genetics

Volume: 46, P: 669-677
Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function

Martin Tobin and colleagues report a meta-analysis of 23 genome-wide association studies for pulmonary function. They identify 16 loci newly associated with variation in two cross-sectional measures of lung function, used to define airway obstruction and to grade the severity of obstruction.

María Soler Artigas
Daan W Loth
Martin D Tobin
Research25 Sept 2011
Nature Genetics

Volume: 43, P: 1082-1090
Characterization of growth differentiation factor 15 (GDF15) as a neurotropic adipokine permeable to the brain

Andreas Schmid
Emily Wilfurth
Andreas Schäffler
ResearchOpen Access17 Aug 2025
Scientific Reports

Volume: 15, P: 1-12

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Blood–brain barrier permeability of adipokines and myokines

Projection map of aquaporin-1 determined by electron crystallography

Dynamics of the human bile acid metabolome during weight loss

Fostering the exchange of real world data across different countries to answer primary care research questions: an UNLOCK study from the IPCRG

Genome-wide association analysis identifies six new loci associated with forced vital capacity

Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function

Characterization of growth differentiation factor 15 (GDF15) as a neurotropic adipokine permeable to the brain

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