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Showing 1–22 of 22 results
Advanced filters: Author: Thomas Lendl Clear advanced filters
  • Time-series observations from the JWST of the transiting exoplanet WASP-39b show gaseous water in the planet’s atmosphere and place an upper limit on the abundance of methane.

    • Eva-Maria Ahrer
    • Kevin B. Stevenson
    • Xi Zhang
    ResearchOpen Access
    Nature
    Volume: 614, P: 653-658
  • The transmission spectrum of the exoplanet WASP-39b is obtained using observations from the Single-Object Slitless Spectroscopy mode of the Near Infrared Imager and Slitless Spectrograph instrument aboard the JWST.

    • Adina D. Feinstein
    • Michael Radica
    • Xi Zhang
    ResearchOpen Access
    Nature
    Volume: 614, P: 670-675
  • The dayside thermal emission spectrum and brightness temperature map of the ultra-hot Jupiter WASP-18b obtained from the NIRISS instrument on the JWST showed water emission features, an atmosphere consistent with solar metallicity, as well as a steep and symmetrical decrease in temperature towards the nightside.

    • Louis-Philippe Coulombe
    • Björn Benneke
    • Peter J. Wheatley
    ResearchOpen Access
    Nature
    Volume: 620, P: 292-298
  • Observations from the JWST show the presence of a spectral absorption feature at 4.05 μm arising from SO2 in the atmosphere of the gas giant exoplanet WASP-39b, which is produced by photochemical processes and verified by numerical models.

    • Shang-Min Tsai
    • Elspeth K. H. Lee
    • Sergei N. Yurchenko
    ResearchOpen Access
    Nature
    Volume: 617, P: 483-487
  • Crosslinking mass spectrometry (XL-MS) has become a crucial tool for studying protein structures and interactions in their native environments, however, the current cleavable linkers are fraught with practical limitations. Here, the authors synthesize and characterize DiSPASO, a novel lysine-reactive, MS-cleavable, and membrane-permeable crosslinker with an alkyne-based click chemistry handle for affinity enrichment, showing potential for improving protein-protein interaction mapping.

    • Fränze Müller
    • Bogdan R. Brutiu
    • Karl Mechtler
    ResearchOpen Access
    Communications Chemistry
    Volume: 8, P: 1-15
  • Phase-resolved mid-infrared observations from JWST of the hot gas giant WASP-43b detect a day–night difference of 659 ± 19 K. Comparison with climate models shows that the observations are compatible with cloudy skies, at least on the nightside, and the lack of methane detection suggests the presence of disequilibrium chemistry.

    • Taylor J. Bell
    • Nicolas Crouzet
    • Sebastian Zieba
    ResearchOpen Access
    Nature Astronomy
    Volume: 8, P: 879-898
  • The medium-resolution transmission spectrum of the exoplanet WASP-39b, described using observations from the Near Infrared Spectrograph G395H grating aboard JWST, shows significant absorption from CO2 and H2O and detection of SO2.

    • Lili Alderson
    • Hannah R. Wakeford
    • Xi Zhang
    ResearchOpen Access
    Nature
    Volume: 614, P: 664-669
  • Observations of six transiting planets around the bright nearby star HD 110067 show that they follow a chain of resonant orbits, with three of the planets inferring the presence of large hydrogen-dominated atmospheres.

    • R. Luque
    • H. P. Osborn
    • T. Zingales
    Research
    Nature
    Volume: 623, P: 932-937
  • Transmission spectroscopy observations from the James Webb Space Telescope show the detection of carbon dioxide in the atmosphere of the gas giant exoplanet WASP-39b.

    • Eva-Maria Ahrer
    • Lili Alderson
    • Sebastian Zieba
    ResearchOpen Access
    Nature
    Volume: 614, P: 649-652
  • We develop a high-throughput CRISPR screening system in cerebral organoids and identify vulnerable cell types and gene regulatory networks associated with autism spectrum disorder from single-cell transcriptomes and chromatin modalities.

    • Chong Li
    • Jonas Simon Fleck
    • Juergen A. Knoblich
    ResearchOpen Access
    Nature
    Volume: 621, P: 373-380
  • The inhibitor of apoptosis (IAP) protein, BRUCE is known to ubiquitinate apoptosis regulators for proteasomal degradation. Here the authors show that BRUCE provides a bridge between LAMP2 on lysosomes and Atg8 family proteins on autophagosomes to support autophagosome-lysosome fusion.

    • Petra Ebner
    • Isabella Poetsch
    • Fumiyo Ikeda
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-15
  • Unpredicted aversive experiences activate DA neurons in dorsal tegmentum; these neurons are important for fear learning. This prediction-error circuit module linking amygdala and dorsal tegmentum enables a solution to an associative learning problem.

    • Florian Groessl
    • Thomas Munsch
    • Wulf Haubensak
    Research
    Nature Neuroscience
    Volume: 21, P: 952-962
  • Three planets orbit the Sun-like star ν2 Lupi. CHEOPS data show that all of them are transiting and show remarkable diversity. In particular, dry and gas-poor inner planet b has experienced extensive atmospheric loss, while planets c and d are water rich and have a small gaseous envelope of primordial origin.

    • Laetitia Delrez
    • David Ehrenreich
    • Nicholas A. Walton
    Research
    Nature Astronomy
    Volume: 5, P: 775-787
  • BET bromodomain inhibitors are being explored as potential therapeutics in cancer; here, AML cells are shown to evade sensitivity to BET inhibition through rewiring the transcriptional regulation of BRD4 target genes such as MYC in a process that is facilitated by suppression of PRC2 and WNT signalling activation.

    • Philipp Rathert
    • Mareike Roth
    • Johannes Zuber
    Research
    Nature
    Volume: 525, P: 543-547