Advanced search

Filter By:

Journal Check one or more journals to show results from those journals only.

Choose more journals

Article type Check one or more article types to show results from those article types only.
Subject Check one or more subjects to show results from those subjects only.
Date Choose a date option to show results from those dates only.

Custom date range

Clear all filters
Sort by:
Showing 1–9 of 9 results
Advanced filters: Author: Thomas Mangeat Clear advanced filters

  • The adhesion of meningococci to endothelial cells relies on type IV pili, which induce the formation of long tubular structures on the host cell membrane. Here, the authors show that the tubular structures accumulate and trap host membrane-associated proteins, which facilitates their interaction with bacterial ligands and the activation of adhesion and signaling receptors.

    • Audrey Laurent-Granger
    • Kévin Sollier
    • Mathieu Coureuil
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-17

  • After the production of double-stranded breaks in mammalian cells, ATM drives the formation of the D compartment, which regulates DNA damage-responsive genes, through the clustering of damaged topologically associating domains, with a mechanism that is consistent with polymer–polymer phase separation.

    • Coline Arnould
    • Vincent Rocher
    • Gaëlle Legube
    ResearchOpen Access
    Nature
    Volume: 623, P: 183-192

  • Actin filaments generate force in diverse contexts, although how they can produce nanonewtons of force is unclear. Here, the authors apply cryo-electron tomography, quantitative analysis, and modelling to reveal the podosome core is a dense, spring-loaded, actin network storing elastic energy.

    • Marion Jasnin
    • Jordan Hervy
    • Renaud Poincloux
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-11

  • The actomyosin cytoskeleton is known to spontaneously oscillate in many systems but the mechanism of this behavior is not clear. Here Qin et al. define a signaling network involving a ROCK-dependent self-activation loop and recruitment of myosin II to the cortex, followed by a local accumulation of myosin phosphatase that shuts off the signal.

    • Xiang Qin
    • Edouard Hannezo
    • Xiaobo Wang
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-15

  • Apoptotic cell death is required for morphogenesis of the developing leg joint of fruitflies; using this model system, the authors show here that within apoptotic cells a transient pulling force exerted through a highly dynamic apico-basal myosin II cable-like structure acts as a mechanical signal to increase tissue tension and modify tissue shape.

    • Bruno Monier
    • Melanie Gettings
    • Magali Suzanne
    Research
    Nature
    Volume: 518, P: 245-248