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Showing 1–4 of 4 results
Advanced filters: Author: Thomas Papouin Clear advanced filters

  • Theta range oscillations in the basolateral amygdala (BLA) and the medial prefrontal cortex (mPFC) are associated with conditioned fear. Here, the authors use exogenous oscillatory stimulation of the BLA and mPFC in mice to determine the dynamic roles of theta-range oscillatory states across conditioned fear and extinction learning.

    • Minagi Ozawa
    • Patrick Davis
    • Leon Reijmers
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-16

  • Mutations of α2-Na/K ATPase can cause familial hemiplegic migraine via unclear mechanisms. Here, the authors show that deletion of α2-Na/K ATPase in astrocytes results in gene expression and metabolic changes leading to cortical spreading depression and episodic transient motor paralysis in mice.

    • Sarah E. Smith
    • Xiaoying Chen
    • Azad Bonni
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-15

  • Recent progress in astrocyte biology requires a more cohesive conceptual framework. This Perspective introduces a ‘contextual guidance’ paradigm in which astrocytes are key to adaptive modeling of neural circuits in response to state changes.

    • Ciaran Murphy-Royal
    • ShiNung Ching
    • Thomas Papouin
    Reviews
    Nature Neuroscience
    Volume: 26, P: 1848-1856

  • The involvement of astroglia in long-term potentiation (LTP) of synaptic transmission remains controversial. Clamping internal Ca2+ in individual astrocytes in the CA1 area of the hippocampus is now shown to block LTP induction at nearby excitatory synapses through an effect on the N-methyl-D-aspartate receptor. This LTP blockade can be reversed by exogenous D-serine, normally released in a Ca2+-dependent manner from astrocytes.

    • Christian Henneberger
    • Thomas Papouin
    • Dmitri A. Rusakov
    Research
    Nature
    Volume: 463, P: 232-236