Many methods are available for colorectal cancer (CRC) screening, ranging from noninvasive stool tests to endoscopy. In this Review, E. J. Kuipers et al. argue that the strength of any single test must be viewed in the context of a range of factors across the screening programme, including test characteristics, uptake, screenee autonomy, cost, endoscopy performance and long-term follow-up.
- Ernst J. Kuipers
- Thomas Rösch
- Michael Bretthauer