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Showing 1–8 of 8 results
Advanced filters: Author: Thomas Seisen Clear advanced filters

  • This article provides consensus-based statements from an international panel of bladder cancer experts on the use of active surveillance in non-muscle invasive bladder cancer. Consensus statements cover several aspects of active surveillance, including terminology, eligibility criteria and treatment triggers, providing a framework to guide clinical practice and trial design in this space.

    • Roberto Contieri
    • Paolo Gontero
    • Laura S. Mertens
    Reviews
    Nature Reviews Urology
    P: 1-6

  • Early use of salvage radiotherapy in patients with prostate cancer with biochemical recurrence after radical prostatectomy has consistently been shown to provide better oncological outcomes than late use. However, the corresponding scientific literature might be subject to lead-time bias, given that in virtually all the available comparative studies, investigators calculated the survival period of included patients from the time of salvage radiotherapy — instead of from the time of radical prostatectomy.

    • Thomas Seisen
    • Quoc-Dien Trinh
    • Firas Abdollah
    Comments & Opinion
    Nature Reviews Urology
    Volume: 14, P: 193-194

  • Radical nephroureterectomy has traditionally been the standard-of-care treatment for most patients with upper tract urothelial carcinomas (UTUCs). However, patients with normal kidney function might benefit from treatment with a kidney-sparing approach. Here, Morgan Rouprêt and colleagues describe the risk-adjusted, kidney-sparing treatment and management of patients with UTUCs and the associated risks and benefits, whilst also highlighting the indications for use of such an approach.

    • Thomas Seisen
    • Pierre Colin
    • Morgan Rouprêt
    Reviews
    Nature Reviews Urology
    Volume: 12, P: 155-166

  • Muscle-invasive bladder cancer with clinically positive pelvic lymph nodes is a particular situation at the interface between localized and metastatic disease. In this Review, the authors discuss the advances and challenges of currently available strategies for the diagnosis and treatment of patients with muscle-invasive bladder cancer with clinically positive pelvic lymph nodes.

    • Elisabeth Grobet-Jeandin
    • Louis Lenfant
    • Thomas Seisen
    Reviews
    Nature Reviews Urology
    Volume: 21, P: 339-356

  • Health-related quality of life can be affected by muscle-invasive bladder cancer treatment and should be assessed all the way through patient’s care. In this Review, the authors summarize available data on patient health-related quality of life after curative local treatment for muscle-invasive bladder cancer, also considering the effect of different surgical procedures or urinary diversion methods on patient quality of life.

    • Elisabeth Grobet-Jeandin
    • Ugo Pinar
    • Thomas Seisen
    Reviews
    Nature Reviews Urology
    Volume: 20, P: 279-293

  • Prostate Cancer Diagnosis and Treatment Enhancement Through the Power of Big Data in Europe (PIONEER) is a European network of excellence for big data in prostate cancer, consisting of 32 private and public stakeholders from 9 countries across Europe. In this Perspectives article, the authors introduce the PIONEER project and describe its aims and plans for ultimately improving prostate cancer care through the use of big data.

    • Muhammad Imran Omar
    • Monique J. Roobol
    • Nazanin Zounemat Kermani
    Reviews
    Nature Reviews Urology
    Volume: 17, P: 351-362