Nature Search

ER aminopeptidases generate a unique pool of peptides for MHC class I molecules

Thomas Serwold
Stephanie Gaw
Nilabh Shastri
Research01 Jul 2001
Nature Immunology

Volume: 2, P: 644-651
ERAAP customizes peptides for MHC class I molecules in the endoplasmic reticulum

Thomas Serwold
Federico Gonzalez
Nilabh Shastri
Research03 Oct 2002
Nature

Volume: 419, P: 480-483
Brown adipose tissue-derived MaR2 contributes to cold-induced resolution of inflammation

Sugimoto et al. show that maresin 2, a specialized pro-resolving mediator that is secreted from brown adipose tissue upon cold exposure, contributes to amelioration of obesity-induced inflammation.

Satoru Sugimoto
Hebe Agustina Mena
Yu-Hua Tseng
Research27 Jun 2022
Nature Metabolism

Volume: 4, P: 775-790
Increased β-cell proliferation before immune cell invasion prevents progression of type 1 diabetes

Type 1 diabetes (T1D) involves immune-mediated destruction of pancreatic β cells. Here, the authors show that inducing β-cell replication before immune cell infiltration of the pancreas alters β-cell antigen expression and prevents T1D disease progression in female NOD mice in a regulatory-T-cell-dependent manner.

Ercument Dirice
Sevim Kahraman
Rohit N. Kulkarni
Research06 May 2019
Nature Metabolism

Volume: 1, P: 509-518
Comprehensive methylome map of lineage commitment from haematopoietic progenitors

During haematopoiesis, multipotent progenitors differentiate into progressively restricted myeloid or lymphoid progenitors. A comprehensive genome-wide DNA methylation analysis of haematopoietic cell populations with well-characterized differentiation potentials reveals remarkable epigenetic plasticity during lymphoid and myeloid restriction.

Hong Ji
Lauren I. R. Ehrlich
Andrew P. Feinberg
Research15 Aug 2010
Nature

Volume: 467, P: 338-342

Quick links

Search

Filter By:

ER aminopeptidases generate a unique pool of peptides for MHC class I molecules

ERAAP customizes peptides for MHC class I molecules in the endoplasmic reticulum

Brown adipose tissue-derived MaR2 contributes to cold-induced resolution of inflammation

Increased β-cell proliferation before immune cell invasion prevents progression of type 1 diabetes

Comprehensive methylome map of lineage commitment from haematopoietic progenitors

Search

Quick links