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Showing 1–3 of 3 results
Advanced filters: Author: Thomas Thestrup Clear advanced filters
  • Juxtaglomerular neurons (JGNs) of the mammalian olfactory bulb are generated throughout life, but when and how these adult-born cells acquire responsiveness to sensory stimuli remains unknown. Here, the authors use in vivotwo-photon imaging to monitor the migration and integration of adult-born JGNs and their sensory response properties.

    • Yury Kovalchuk
    • Ryota Homma
    • Olga Garaschuk
    Research
    Nature Communications
    Volume: 6, P: 1-12
  • Marsilius Mues et al. have overcome previous obstacles precluding the expression of genetically encoded calcium indicators (GECIs) in immune cells by developing a new fluorescence resonance energy transfer–based GECI for the functional calcium imaging of T cells in vivo. Using two-photon imaging, the group traced the real-time activation of T cells in peripheral lymph nodes after antigen application, as well as in the CNS during experimental autoimmune encephalomyelitis.

    • Marsilius Mues
    • Ingo Bartholomäus
    • Gurumoorthy Krishnamoorthy
    Research
    Nature Medicine
    Volume: 19, P: 778-783