Proteins that are translocated across the endoplasmic reticulum (ER) membrane may be subject to glycosylation during transport. Using cryoelectron microscopy of native ER membranes, Pfeffer et al.map the location of oligosaccharyl-transferase within the translocon, providing insight into how these processes are coupled.
- Stefan Pfeffer
- Johanna Dudek
- Friedrich Förster