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Showing 1–12 of 12 results
Advanced filters: Author: Thomas Zhihao Luo Clear advanced filters

  • Simultaneous recordings were made of hundreds of neurons in the rat frontal cortex and striatum, showing that decision commitment involves a rapid, coordinated transition in dynamical regime and neural mode.

    • Thomas Zhihao Luo
    • Timothy Doyeon Kim
    • Carlos D. Brody
    ResearchOpen Access
    Nature
    Volume: 646, P: 1156-1166

  • The evolutionary reasons for the variation in silicon concentrations across plant families remain unclear. This paper provides new evidence that silicon variation is closely linked to global and long-term climate change, suggesting temperature could have driven the evolution of plant silicification.

    • Zhihao Pang
    • Félix de Tombeur
    • Yongchao Liang
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-13

  • Narcolepsy has genetic and environmental risk factors, but the specific genetic risk loci and interaction with environmental triggers are not well understood. Here, the authors identify genetic loci for narcolepsy, suggesting infection as a trigger and dendritic and helper T cell involvement.

    • Hanna M. Ollila
    • Eilon Sharon
    • Emmanuel J. Mignot
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-13

  • A genome-wide association study suggests 41 previously unreported loci on top of the 23 known loci that influence the disease risk for lumbar disc herniations. Many of these loci harbour genes implicated in disc structure and inflammation, as well as genes related to the nervous system and nerve function.

    • Ville Salo
    • Juhani Määttä
    • Johannes Kettunen
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-14

  • Many genetic factors that contribute to uterine leiomyomata (UL) - the most common tumours of the female genital tract - remain to be discovered. Here, the authors conduct a UL meta-genome-wide association study, and find loci related to altered muscle tissue biology that are associated with UL.

    • Eeva Sliz
    • Jaakko S. Tyrmi
    • Johannes Kettunen
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-14

  • In an inter-laboratory study, the authors compare the accuracy and performance of three optical density calibration protocols (colloidal silica, serial dilution of silica microspheres, and colony-forming unit (CFU) assay). They demonstrate that serial dilution of silica microspheres is the best of these tested protocols, allowing precise and robust calibration that is easily assessed for quality control and can also evaluate the effective linear range of an instrument.

    • Jacob Beal
    • Natalie G. Farny
    • Jiajie Zhou
    ResearchOpen Access
    Communications Biology
    Volume: 3, P: 1-29

  • The largest meta-analysis of GWASs of hepcidin and sTfR identified 43 genomic loci, of which 15 new. Mendelian randomisation revealed associations of systemic iron status and iron-related loci with selected health outcomes across multiple domains.

    • Elias Allara
    • Steven Bell
    • Emanuele Di Angelantonio
    ResearchOpen Access
    Communications Biology
    Volume: 7, P: 1-17