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Showing 1–2 of 2 results
Advanced filters: Author: Tim Düking Clear advanced filters

  • Stromal cells are key players in immune cell homeostasis. Here, the authors decipher subset-specific human stromal responses in inflammatory bowel disease and suggest that intestinal PDGFRA+CD142−/low fibroblasts guide monocyte transition to macrophages in human gut through GM-CSF.

    • Egle Kvedaraite
    • Magda Lourda
    • Mattias Svensson
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-16

  • Efficient repair of demyelinated CNS lesions involves the resolution of inflammation and induction of remyelination. Berghoff et al. show that sterol synthesis in microglia is key to both processes, which can be supported by squalene therapy.

    • Stefan A. Berghoff
    • Lena Spieth
    • Gesine Saher
    Research
    Nature Neuroscience
    Volume: 24, P: 47-60