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Showing 1–15 of 15 results
Advanced filters: Author: Tim Daw Clear advanced filters

  • A large genome-wide association study of more than 5 million individuals reveals that 12,111 single-nucleotide polymorphisms account for nearly all the heritability of height attributable to common genetic variants.

    • Loïc Yengo
    • Sailaja Vedantam
    • Joel N. Hirschhorn
    ResearchOpen Access
    Nature
    Volume: 610, P: 704-712

  • A genome-wide association meta-analysis study of blood lipid levels in roughly 1.6 million individuals demonstrates the gain of power attained when diverse ancestries are included to improve fine-mapping and polygenic score generation, with gains in locus discovery related to sample size.

    • Sarah E. Graham
    • Shoa L. Clarke
    • Cristen J. Willer
    Research
    Nature
    Volume: 600, P: 675-679

  • A study proposes four ways in which foods sourced in aquatic environments can contribute to healthier, more environmentally sustainable and equitable food systems, and examines the relevance of these ambitions to nations.

    • Beatrice I. Crona
    • Emmy Wassénius
    • Colette C. C. Wabnitz
    ResearchOpen Access
    Nature
    Volume: 616, P: 104-112

  • Timothy Frayling, Joel Hirschhorn, Peter Visscher and colleagues report a meta-analysis of genome-wide association studies for adult height in 253,288 individuals. They identify 697 variants in 423 loci significantly associated with adult height and find that these variants cluster in pathways involved in growth and together explain one-fifth of the heritability for this trait.

    • Andrew R Wood
    • Tonu Esko
    • Timothy M Frayling
    Research
    Nature Genetics
    Volume: 46, P: 1173-1186

  • An analysis of quantitative sociological data reveals that adaptive capacity has increased in coastal fishing communities in Kenya, but that underprivileged segments of society remain vulnerable to the impacts of climate change.

    • Joshua E. Cinner
    • Cindy Huchery
    • Edward H. Allison
    Research
    Nature Climate Change
    Volume: 5, P: 872-876

  • Genome-wide association meta-analyses of waist-to-hip ratio adjusted for body mass index in more than 224,000 individuals identify 49 loci, 33 of which are new and many showing significant sexual dimorphism with a stronger effect in women; pathway analyses implicate adipogenesis, angiogenesis, transcriptional regulation and insulin resistance as processes affecting fat distribution.

    • Dmitry Shungin
    • Thomas W. Winkler
    • Karen L Mohlke
    Research
    Nature
    Volume: 518, P: 187-196

  • A genome-wide association study and Metabochip meta-analysis of body mass index (BMI) detects 97 BMI-associated loci, of which 56 were novel, and many loci have effects on other metabolic phenotypes; pathway analyses implicate the central nervous system in obesity susceptibility and new pathways such as those related to synaptic function, energy metabolism, lipid biology and adipogenesis.

    • Adam E. Locke
    • Bratati Kahali
    • Elizabeth K. Speliotes
    Research
    Nature
    Volume: 518, P: 197-206

  • Well-being and resilience are considered related or even synergistic dimensions of sustainable development. This Perspective highlights how trade-offs emerging from narrow interpretations of resilience and well-being could threaten sustainable development outcomes.

    • Tomas Chaigneau
    • Sarah Coulthard
    • Katrina Brown
    Reviews
    Nature Sustainability
    Volume: 5, P: 287-293

  • Sonnemann and colleagues use Bayesian inference to obtain seabed geoacoustic properties. Their method allows resolving up to 10 cm thin sediment layers over wide areas.

    • Tim Sonnemann
    • Jan Dettmer
    • Stan E. Dosso
    ResearchOpen Access
    Communications Engineering
    Volume: 3, P: 1-10

  • Microbubbles show great promise in clinical application as diagnostic ultrasound contrast agents. Chabouh and coworkers characterize the swimming motion of these microbubbles under cyclic external pressures through buckling. The results provide guidance to design ultrasound contrast agents with accurate mobility control.

    • Georges Chabouh
    • Marcel Mokbel
    • Gwennou Coupier
    ResearchOpen Access
    Communications Engineering
    Volume: 2, P: 1-8

  • Numerical tools for flood forecasting and for designing coastal protection schemes require accurate real world data on speed and volume of overtopping waves on sea walls. Margaret Yelland and colleagues here describe the validation and field deployment of arrays of capacitance sensors, termed Wirewall, as a tool for acquisition of detailed data of coastal overtopping.

    • Margaret J. Yelland
    • Jennifer M. Brown
    • Eunice Silva
    ResearchOpen Access
    Communications Engineering
    Volume: 2, P: 1-13