During synthesis, modification and maturation of the ribosomal RNA, correct subdomain folding without additional guidance poses a major challenge. Here, the authors observe the snR30 H/ACA snoRNP forming a “satellite particle” with the 90S, the earliest known pre-ribosome, where localized structural interactions guide its independent folding.
- Paulina Fischer
- Matthias Thoms
- Roland Beckmann
