Cell division and cilium formation are dependent on centrosomes that consist of two centrioles and pericentriolar material (PCM). In this study, the Sas-4 protein is shown to be important in mediating the formation of cytoplasmic PCM complexes and the incorporation of this material into centrosomes.
- Jayachandran Gopalakrishnan
- Vito Mennella
- Tomer Avidor-Reiss