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Showing 351–400 of 462 results

Advanced filters: Author: Timothy P. Ryan Clear advanced filters

Exploratory digital outcome measures of motor sign progression in Parkinson’s disease patients treated with prasinezumab

Kirsten I. Taylor
Florian Lipsmeier
Stefano Zanigni
ResearchOpen Access16 Jun 2025
npj Digital Medicine

Volume: 8, P: 1-12
FORCE platform overcomes barriers of oligonucleotide delivery to muscle and corrects myotonic dystrophy features in preclinical models

Weeden et al. use a method called FORCE to deliver oligonucleotides to muscle and evaluate the platform’s utility in models of myotonic dystrophy. An antisense oligonucleotide targeting DMPK is guided to muscle tissue with an antibody fragment and beneficial results are seen in mouse models of disease and cynomolgus monkey.

Timothy Weeden
Tyler Picariello
Stefano Zanotti
ResearchOpen Access18 Jan 2025
Communications Medicine

Volume: 5, P: 1-18
Immunogenicity and efficacy of mRNA COVID-19 vaccine MRT5500 in preclinical animal models

Kirill V. Kalnin
Timothy Plitnik
Danilo Casimiro
ResearchOpen Access19 Apr 2021
npj Vaccines

Volume: 6, P: 1-12
Neurodevelopmental outcome of preterm infants enrolled in myo-inositol randomized controlled trial

Ira Adams-Chapman
Kristi L. Watterberg
Marian Willinger
Research23 Mar 2021
Journal of Perinatology

Volume: 41, P: 2072-2087
Bone marrow transplantation increases sulfatase activity in somatic tissues in a multiple sulfatase deficiency mouse model

Presa et al. use a mouse model of multiple sulfatase deficiency (MSD) to assess efficacy of bone marrow transplantation to increase sulfatase activity. Sulfatase activity is partially restored in some peripheral tissues such as spleen, liver and heart, but no significant benefit is observed in the brain.

Maximiliano Presa
Vi Pham
Cathleen Lutz
ResearchOpen Access25 Oct 2024
Communications Medicine

Volume: 4, P: 1-12
Author Correction: SARS-CoV-2 evolution during treatment of chronic infection

Steven A. Kemp
Dami A. Collier
Ravindra K. Gupta
Amendments and Corrections21 Jul 2022
Nature

Volume: 608, P: E23
Addendum: The mutational constraint spectrum quantified from variation in 141,456 humans

Sanna Gudmundsson
Konrad J. Karczewski
Daniel G. MacArthur
Amendments and CorrectionsOpen Access09 Aug 2021
Nature

Volume: 597, P: E3-E4
Author Correction: Convalescent plasma for hospitalized patients with COVID-19: an open-label, randomized controlled trial

Philippe Bégin
Jeannie Callum
Donald M. Arnold
Amendments and CorrectionsOpen Access12 Jan 2022
Nature Medicine

Volume: 28, P: 212
Author Correction: Sensitivity of SARS-CoV-2 B.1.1.7 to mRNA vaccine-elicited antibodies

Dami A. Collier
Anna De Marco
Ravindra K. Gupta
Amendments and Corrections21 Jul 2022
Nature

Volume: 608, P: E24
Author Correction: Expanded encyclopaedias of DNA elements in the human and mouse genomes

Federico Abascal
Reyes Acosta
Zhiping Weng
Amendments and CorrectionsOpen Access26 Apr 2022
Nature

Volume: 605, P: E3
Author Correction: Adaptive platform trials: definition, design, conduct and reporting considerations

Derek C. Angus
Brian M. Alexander
Janet Woodcock
Amendments and Corrections10 Sept 2019
Nature Reviews Drug Discovery

Volume: 18, P: 808
Publisher Correction: Genomic reconstruction of the SARS CoV-2 epidemic in England

Harald S. Vöhringer
Theo Sanderson
Moritz Gerstung
Amendments and CorrectionsOpen Access07 Jun 2022
Nature

Volume: 606, P: E18
Towards pharmacokinetic boosting of phenoxymethylpenicillin (penicillin-V) using probenecid for the treatment of bacterial infections

Richard C. Wilson
Alaa Riezk
Timothy M. Rawson
ResearchOpen Access21 Jul 2024
Scientific Reports

Volume: 14, P: 1-10
Behavioral changes and growth deficits in a CRISPR engineered mouse model of the schizophrenia-associated 3q29 deletion

Timothy P. Rutkowski
Ryan H. Purcell
Jennifer Gladys Mulle
Research11 Apr 2019
Molecular Psychiatry

Volume: 26, P: 772-783
Impact of alcohol exposure on neural development and network formation in human cortical organoids

Jason W. Adams
Priscilla D. Negraes
Cleber A. Trujillo
ResearchOpen Access16 Nov 2022
Molecular Psychiatry

Volume: 28, P: 1571-1584
Morphological and evolutionary insights into the keystone element of the human foot’s medial longitudinal arch

A GM study diachronically examined evolution of the medial longitudinal arch and variation as expressed by the navicular bone, identifying navicular traits associated with particular locomotor behaviors, subsistence strategies, and foot types

Rita Sorrentino
Kristian J. Carlson
Stefano Benazzi
ResearchOpen Access19 Oct 2023
Communications Biology

Volume: 6, P: 1-13
Surfactant Administration by Transient Intubation in Infants 29 to 35 Weeks' Gestation with Respiratory Distress Syndrome Decreases the Likelihood of Later Mechanical Ventilation: A Randomized Controlled Trial

Ann Reininger
Rubia Khalak
Carl T D'Angio
Research15 Sept 2005
Journal of Perinatology

Volume: 25, P: 703-708
Preclinical Development of a Fusion Peptide Conjugate as an HIV Vaccine Immunogen

Li Ou
Wing-Pui Kong
Peter D. Kwong
ResearchOpen Access20 Feb 2020
Scientific Reports

Volume: 10, P: 1-13
Author Correction: Inherited causes of clonal haematopoiesis in 97,691 whole genomes

Alexander G. Bick
Joshua S. Weinstock
Pradeep Natarajan
Amendments and Corrections11 Mar 2021
Nature

Volume: 591, P: E27
Racial and ethnic differences in prenatal exposure to environmental phenols and parabens in the ECHO Cohort

Michael S. Bloom
Sudhi Upadhyaya
Lynne M. Smith
ResearchOpen Access15 Feb 2025
Journal of Exposure Science & Environmental Epidemiology

Volume: 35, P: 992-1002
Altered network and rescue of human neurons derived from individuals with early-onset genetic epilepsy

Priscilla D. Negraes
Cleber A. Trujillo
Alysson R. Muotri
ResearchOpen Access22 Apr 2021
Molecular Psychiatry

Volume: 26, P: 7047-7068
Oxygen loss from seagrass roots coincides with colonisation of sulphide-oxidising cable bacteria and reduces sulphide stress

Belinda C. Martin
Jeremy Bougoure
Gary A. Kendrick
Research23 Oct 2018
The ISME Journal

Volume: 13, P: 707-719
Long-term stability of computational parameters during approach-avoidance conflict in a transdiagnostic psychiatric patient sample

Ryan Smith
Namik Kirlic
Robin L. Aupperle
ResearchOpen Access03 Jun 2021
Scientific Reports

Volume: 11, P: 1-13
Reply to: Concerns about estimating relative risk of death associated with convalescent plasma for COVID-19

Philippe Bégin
Jeannie Callum
Donald M. Arnold
Research10 Jan 2022
Nature Medicine

Volume: 28, P: 53-58
Correlates of compliance with recommended levels of physical activity in children

Thayse Natacha Gomes
Peter T. Katzmarzyk
José Maia
ResearchOpen Access28 Nov 2017
Scientific Reports

Volume: 7, P: 1-11
Non-invasive biomarkers for detecting progression toward hypovolemic cardiovascular instability in a lower body negative pressure model

Ethan K. Murphy
Spencer R. Bertsch
Norman A. Paradis
ResearchOpen Access15 Apr 2024
Scientific Reports

Volume: 14, P: 1-10
Surgical gestures as a method to quantify surgical performance and predict patient outcomes

Runzhuo Ma
Ashwin Ramaswamy
Andrew J. Hung
ResearchOpen Access22 Dec 2022
npj Digital Medicine

Volume: 5, P: 1-8
Temperature contributes to host specialization of coffee wilt disease (Fusarium xylarioides) on arabica and robusta coffee crops

Xiuhan Zhang
Lily D. Peck
Timothy G. Barraclough
ResearchOpen Access08 Jun 2023
Scientific Reports

Volume: 13, P: 1-12
Comparative genomics of Alexander Fleming’s original Penicillium isolate (IMI 15378) reveals sequence divergence of penicillin synthesis genes

Ayush Pathak
Reuben W. Nowell
Timothy G. Barraclough
ResearchOpen Access24 Sept 2020
Scientific Reports

Volume: 10, P: 1-10
BACE1 across species: a comparison of the in vivo consequences of BACE1 deletion in mice and rats

Martin Weber
Tiffany Wu
Kimberly Scearce-Levie
ResearchOpen Access10 Mar 2017
Scientific Reports

Volume: 7, P: 1-17
Author Correction: Federated learning enables big data for rare cancer boundary detection

Sarthak Pati
Ujjwal Baid
Spyridon Bakas
Amendments and CorrectionsOpen Access26 Jan 2023
Nature Communications

Volume: 14, P: 1-2
Publisher Correction: SARS-CoV-2 Omicron is an immune escape variant with an altered cell entry pathway

Brian J. Willett
Joe Grove
Emma C. Thomson
Amendments and CorrectionsOpen Access16 Sept 2022
Nature Microbiology

Volume: 7, P: 1709
Whole genome sequencing of amplified Plasmodium knowlesi DNA from unprocessed blood reveals genetic exchange events between Malaysian Peninsular and Borneo subpopulations

Ernest Diez Benavente
Ana Rita Gomes
Susana Campino
ResearchOpen Access08 Jul 2019
Scientific Reports

Volume: 9, P: 1-11
Enzyme-linked DNA dendrimer nanosensors for acetylcholine

Ryan Walsh
Jennifer M. Morales
Heather A. Clark
ResearchOpen Access07 Oct 2015
Scientific Reports

Volume: 5, P: 1-11
Distinct blood inflammatory biomarker clusters stratify host phenotypes during the middle phase of COVID-19

Paul W. Blair
Joost Brandsma
N. Huprikar
ResearchOpen Access28 Dec 2022
Scientific Reports

Volume: 12, P: 1-10
Estimating ambient-origin PM_2.5 exposure for epidemiology: observations, prediction, and validation using personal sampling in the Multi-Ethnic Study of Atherosclerosis

Kristin A. Miller
Elizabeth W. Spalt
Joel D. Kaufman
Research30 Aug 2018
Journal of Exposure Science & Environmental Epidemiology

Volume: 29, P: 227-237
Roles for p53 in growth arrest and apoptosis: putting on the brakes after genotoxic stress

Sally A Amundson
Timothy G Myers
Albert J Fornace Jr
Reviews12 Jan 1999
Oncogene

Volume: 17, P: 3287-3299
Author Correction: Characterising the loss-of-function impact of 5’ untranslated region variants in 15,708 individuals

Nicola Whiffin
Konrad J. Karczewski
James S. Ware
Amendments and CorrectionsOpen Access02 Feb 2021
Nature Communications

Volume: 12, P: 1
Author Correction: Evaluating drug targets through human loss-of-function genetic variation

Eric Vallabh Minikel
Konrad J. Karczewski
Daniel G. MacArthur
Amendments and CorrectionsOpen Access03 Feb 2021
Nature

Volume: 590, P: E56
Metabolic effects of the schizophrenia-associated 3q29 deletion

Rebecca M. Pollak
Ryan H. Purcell
Jennifer G. Mulle
ResearchOpen Access17 Feb 2022
Translational Psychiatry

Volume: 12, P: 1-10
Relationships Between Neuromuscular Function and Functional Balance Performance in Firefighters

Jacob A. Mota
Timothy J. Barnette
Eric D. Ryan
ResearchOpen Access17 Oct 2018
Scientific Reports

Volume: 8, P: 1-8
Metabolome and microbiome profiling of a stress-sensitive rat model of gut-brain axis dysfunction

Shalome A. Bassett
Wayne Young
Nicole C. Roy
ResearchOpen Access01 Oct 2019
Scientific Reports

Volume: 9, P: 1-13
Unveiling errors in soil microbial community sequencing: a case for reference soils and improved diagnostics for nanopore sequencing

A soil bacterial amplicon sequencing study using the Nanopore MinION platform suggests that common diagnostics are insufficient to detect irregular community results and recommends further diagnostics and the use of a reference soil as a mock community.

Daniel K. Manter
Catherine L. Reardon
David B. Knaebel
ResearchOpen Access28 Jul 2024
Communications Biology

Volume: 7, P: 1-13
TCTEX1D1 is a genetic modifier of disease progression in Duchenne muscular dystrophy

Pietro Spitali
Irina Zaharieva
Annemieke Aartsma-Rus
ResearchOpen Access02 Jan 2020
European Journal of Human Genetics

Volume: 28, P: 815-825
Open-Source Remote Gait Analysis: A Post-Surgery Patient Monitoring Application

Reed D. Gurchiek
Rebecca H. Choquette
Ryan S. McGinnis
ResearchOpen Access29 Nov 2019
Scientific Reports

Volume: 9, P: 1-10
Non-invasive diffuse optical neuromonitoring during cardiopulmonary resuscitation predicts return of spontaneous circulation

Tiffany S. Ko
Constantine D. Mavroudis
Todd J. Kilbaugh
ResearchOpen Access15 Feb 2021
Scientific Reports

Volume: 11, P: 1-14
Recombinant Incretin-Secreting Microbe Improves Metabolic Dysfunction in High-Fat Diet Fed Rodents

Paul M. Ryan
Elaine Patterson
R. Paul Ross
ResearchOpen Access19 Oct 2017
Scientific Reports

Volume: 7, P: 1-12
Scientific data from precipitation driver response model intercomparison project

Gunnar Myhre
Bjørn Samset
Duncan Watson-Parris
ResearchOpen Access30 Mar 2022
Scientific Data

Volume: 9, P: 1-7
Transcriptomic adaptation during skeletal muscle habituation to eccentric or concentric exercise training

Craig R. G. Willis
Colleen S. Deane
Timothy Etheridge
ResearchOpen Access14 Dec 2021
Scientific Reports

Volume: 11, P: 1-14
Distinct clinical symptom patterns in patients hospitalised with COVID-19 in an analysis of 59,011 patients in the ISARIC-4C study

Jonathan E. Millar
Lucile Neyton
Peter Young
ResearchOpen Access27 Apr 2022
Scientific Reports

Volume: 12, P: 1-13

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