Advanced search

Filter By:

Journal Check one or more journals to show results from those journals only.

Choose more journals

Article type Check one or more article types to show results from those article types only.
Subject Check one or more subjects to show results from those subjects only.
Date Choose a date option to show results from those dates only.

Custom date range

Clear all filters
Sort by:
Showing 1–50 of 399 results
Advanced filters: Author: Tom Clarke Clear advanced filters

  • When 100 social and behavioural science claims were examined, 34% of reanalyses closely matched the original results, with 74% reaching the same conclusion, revealing limited robustness of single-path analyses and the need to address analytical uncertainty.

    • Balazs Aczel
    • Barnabas Szaszi
    • Brian A. Nosek
    Research
    Nature
    Volume: 652, P: 135-142

  • A global network of researchers was formed to investigate the role of human genetics in SARS-CoV-2 infection and COVID-19 severity; this paper reports 13 genome-wide significant loci and potentially actionable mechanisms in response to infection.

    • Mari E. K. Niemi
    • Juha Karjalainen
    • Chloe Donohue
    ResearchOpen Access
    Nature
    Volume: 600, P: 472-477

  • If wild populations of the mosquito that transmits malaria were replaced with insects rendered harmless by genetic engineering, the disease could finally be defeated. But that remains a big 'if', as Tom Clarke finds out.

    • Tom Clarke
    News
    Nature
    Volume: 419, P: 429-430

  • If wild populations of the mosquito that transmits malaria were replaced with insects rendered harmless by genetic engineering, the disease could finally be defeated. But that remains a big 'if', as Tom Clarke finds out.

    • Tom Clarke
    News
    Nature

  • Sun-like stars may cannibalize the planets that orbit them.

    • Tom Clarke
    News
    Nature

  • Global warming could make the rich richer and the poor poorer.

    • Tom Clarke
    News
    Nature

  • Across continental Europe, historical instruments are falling silent, muted by a new and mysterious form of corrosion. Tom Clarke speaks to the chemical detectives who are striving to protect our musical heritage.

    • Tom Clarke
    News
    Nature
    Volume: 427, P: 8-9

  • Increasingly, the drugs giants are outsourcing research in drug discovery to start-up companies. Tom Clarke and Helen Pearson analyse an emerging trend, and ask what both sides expect to gain.

    • Tom Clarke
    • Helen Pearson
    News
    Nature
    Volume: 414, P: 482-483

  • Clues about the origin and fate of the Universe lie hidden in the microwave radiation left over from its early days. Tom Clarke examines the latest attempts to map the Big Bang's afterglow.

    • Tom Clarke
    News
    Nature
    Volume: 411, P: 880-881

  • An international team of scientists and engineers is in Cameroon to begin 'degassing' Lake Nyos, scene of a 1986 natural disaster in which a cloud of carbon dioxide killed more than 1,700 people. Tom Clarke assesses the risks and benefits.

    • Tom Clarke
    News
    Nature
    Volume: 409, P: 554-555

  • Tom Clarke retraces the path that led Watson and Crick to the double helix, and others to put their discovery to use.

    • Tom Clarke
    News
    Nature

  • Over the coming decade, exploration of Mars may reveal whether or not life ever existed on the red planet — but only if the missions can avoid detecting any microbes they bring with them, says Tom Clarke.

    • Tom Clarke
    News
    Nature
    Volume: 413, P: 247-248

  • An analysis of 24,202 critical cases of COVID-19 identifies potentially druggable targets in inflammatory signalling (JAK1), monocyte–macrophage activation and endothelial permeability (PDE4A), immunometabolism (SLC2A5 and AK5), and host factors required for viral entry and replication (TMPRSS2 and RAB2A).

    • Erola Pairo-Castineira
    • Konrad Rawlik
    • J. Kenneth Baillie
    ResearchOpen Access
    Nature
    Volume: 617, P: 764-768

  • Whole-genome sequencing, transcriptome-wide association and fine-mapping analyses in over 7,000 individuals with critical COVID-19 are used to identify 16 independent variants that are associated with severe illness in COVID-19.

    • Athanasios Kousathanas
    • Erola Pairo-Castineira
    • J. Kenneth Baillie
    ResearchOpen Access
    Nature
    Volume: 607, P: 97-103

  • COVID-19 can be associated with neurological complications. Here the authors show that markers of brain injury, but not immune markers, are elevated in the blood of patients with COVID-19 both early and months after SARS-CoV-2 infection, particularly in those with brain dysfunction or neurological diagnoses.

    • Benedict D. Michael
    • Cordelia Dunai
    • David K. Menon
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-15

  • Dazzling snapshots show how ions power nerve signals round the body.

    • Tom Clarke
    News
    Nature

  • Astronomers suspect star like our Sun when young is giving birth to planets.

    • Tom Clarke
    News
    Nature

  • Earth and Mars were born 20 million years earlier than thought.

    • Tom Clarke
    News
    Nature

  • New photoreceptor throws light on hidden workings of the eye.

    • Tom Clarke
    News
    Nature

  • Four new studies may finally have put paid to the polio-vaccine hypothesis for HIV's origins.

    • Tom Clarke
    News
    Nature

  • This report from the 1000 Genomes Project describes the genomes of 1,092 individuals from 14 human populations, providing a resource for common and low-frequency variant analysis in individuals from diverse populations; hundreds of rare non-coding variants at conserved sites, such as motif-disrupting changes in transcription-factor-binding sites, can be found in each individual.

    • Gil A. McVean
    • David M. Altshuler (Co-Chair)
    • Gil A. McVean
    ResearchOpen Access
    Nature
    Volume: 491, P: 56-65

  • The goal of the 1000 Genomes Project is to provide in-depth information on variation in human genome sequences. In the pilot phase reported here, different strategies for genome-wide sequencing, using high-throughput sequencing platforms, were developed and compared. The resulting data set includes more than 95% of the currently accessible variants found in any individual, and can be used to inform association and functional studies.

    • Richard M. Durbin
    • David Altshuler (Co-Chair)
    • Gil A. McVean
    ResearchOpen Access
    Nature
    Volume: 467, P: 1061-1073

  • A study reports whole-genome sequences for 490,640 participants from the UK Biobank and combines these data with phenotypic data to provide new insights into the relationship between human variation and sequence variation.

    • Keren Carss
    • Bjarni V. Halldorsson
    • Ole Schulz-Trieglaff
    ResearchOpen Access
    Nature
    Volume: 645, P: 692-701