Nature Search

Natural hazard susceptibilities and inequities reduced by short-term groundwater use

The use of groundwater can help mitigate the impacts of natural disasters, thereby increasing the resilience of communities during and after events, according to a synthesis of hydrology and disaster response research.

Tom Gleeson
Takahiro Endo
Giuliano Di Baldassarre
Reviews07 Jan 2026
Nature Geoscience

Volume: 19, P: 12-18
Water balance of global aquifers revealed by groundwater footprint

A newly developed concept called ‘groundwater footprint’ is used to reveal the degree of sustainable use of global aquifers by calculating the area relative to the extractive demands; globally, this footprint exceeds aquifer area by a factor of about 3.5, and excess withdrawal is centred on just a few agriculturally important aquifers.

Tom Gleeson
Yoshihide Wada
Ludovicus P. H. van Beek
Research08 Aug 2012
Nature

Volume: 488, P: 197-200
Regulation and feedback of cholesterol metabolism

William Griffiths
Tom Freeman
Mathieu Blanc
ResearchOpen Access31 Aug 2011
Nature Precedings

P: 1
The RNA Atlas expands the catalog of human non-coding RNAs

The human transcriptome from 300 tissues and cell lines reveals novel non-coding RNAs.

Lucia Lorenzi
Hua-Sheng Chiu
Pieter Mestdagh
Research17 Jun 2021
Nature Biotechnology

Volume: 39, P: 1453-1465
Reply to 'Threats to coastal aquifers'

Grant Ferguson
Tom Gleeson
Correspondence25 Jun 2013
Nature Climate Change

Volume: 3, P: 605-606
Author Correction: The global volume and distribution of modern groundwater

Tom Gleeson
Kevin M. Befus
M. Bayani Cardenas
Amendments and Corrections11 Jun 2018
Nature Geoscience

Volume: 11, P: 542
Groundwater-dependent ecosystem map exposes global dryland protection needs

Mapping of groundwater-dependent ecosystems, which support biodiversity and rural livelihoods, shows they occur on more than one-third of global drylands analysed, but lack protections to safeguard these critical ecosystems and the societies dependent upon them from groundwater depletion.

Melissa M. Rohde
Christine M. Albano
John C. Stella
ResearchOpen Access17 Jul 2024
Nature

Volume: 632, P: 101-107
Groundwater: a call to action

Tom Gleeson
Karen Villholth
David Hyndman
Correspondence02 Dec 2019
Nature

Volume: 576, P: 213
Large-scale phenotyping of patients with long COVID post-hospitalization reveals mechanistic subtypes of disease

Openshaw and colleagues find myeloid inflammation and complement activation signatures in patients with long COVID who were previously hospitalized.

Felicity Liew
Claudia Efstathiou
J. Eunice Zhang
ResearchOpen Access08 Apr 2024
Nature Immunology

Volume: 25, P: 607-621
Notable shifts beyond pre-industrial streamflow and soil moisture conditions transgress the planetary boundary for freshwater change

Exceptional streamflow and soil moisture conditions now occur on a substantial share of global land area and are much more frequent than in pre-industrial times. This marks a notable transgression of the new planetary boundary for freshwater change.

Miina Porkka
Vili Virkki
Matti Kummu
ResearchOpen Access04 Mar 2024
Nature Water

Volume: 2, P: 262-273
Vulnerability of coastal aquifers to groundwater use and climate change

There are concerns that sea-level rise resulting from climate change could lead to saltwater intrusion into coastal aquifers. However, a study shows that groundwater extraction is the main driver of saltwater intrusion in the United States, highlighting the importance of sustainable water management.

Grant Ferguson
Tom Gleeson
Research19 Feb 2012
Nature Climate Change

Volume: 2, P: 342-345
Comparison of rhesus and cynomolgus macaques as an infection model for COVID-19

Non-human primates are important animal models for studying SARS-CoV-2 infection. Here, Salguero et al. directly compare rhesus and cynomolgus macaques and show that both species represent COVID-19 disease of mild clinical cases, and provide a lung histopathology scoring system.

Francisco J. Salguero
Andrew D. White
Miles W. Carroll
ResearchOpen Access24 Feb 2021
Nature Communications

Volume: 12, P: 1-14
SARS-CoV-2-specific immune responses and clinical outcomes after COVID-19 vaccination in patients with immune-suppressive disease

Serological analysis and infection outcomes of participants in the multi-center, prospectively enrolled OCTAVE cohort, comprising 2,686 participants with immune-suppressive diseases who recieved two COVID-19 vaccines, reveals specific clinical phenotypes that might benefit from specific COVID-19 therapeutic strategies.

Eleanor Barnes
Carl S. Goodyear
Deborah Richardson
ResearchOpen Access06 Jul 2023
Nature Medicine

Volume: 29, P: 1760-1774
Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes

Fine-mapping of causal variants and integration of epigenetic and chromatin conformation data identify likely target genes for 150 breast cancer risk regions.

Laura Fachal
Hugues Aschard
Alison M. Dunning
Research07 Jan 2020
Nature Genetics

Volume: 52, P: 56-73
Hotspots for social and ecological impacts from freshwater stress and storage loss

This work identifies the world’s most vulnerable basins to social and ecological impacts from freshwater stress and storage loss: a set of 168 hotspot basins for global prioritization that encompass 1.5 billion people, 17% of global food crops, 13% of global GDP, and hundreds of significant wetlands.

Xander Huggins
Tom Gleeson
James S. Famiglietti
ResearchOpen Access21 Jan 2022
Nature Communications

Volume: 13, P: 1-11
Fresh groundwater discharge insignificant for the world’s oceans but important for coastal ecosystems

The authors here present the global entry of nutrients into marine systems through fresh submarine groundwater discharge to be below 1%. However, they also identify hotspots and argue that about 25% of world’s estuaries are at danger of eutrophication.

Elco Luijendijk
Tom Gleeson
Nils Moosdorf
ResearchOpen Access09 Mar 2020
Nature Communications

Volume: 11, P: 1-12
Global aquifers dominated by fossil groundwaters but wells vulnerable to modern contamination

Groundwater that predates the Holocene is commonly assumed to be unaffected by modern contamination. A global analysis of fossil groundwater suggests that modern contaminants are present in deep wells that tap fossil aquifers.

Scott Jasechko
Debra Perrone
James W. Kirchner
Research25 Apr 2017
Nature Geoscience

Volume: 10, P: 425-429
Relative contribution of monsoon precipitation and pumping to changes in groundwater storage in India

Groundwater storage has declined in northern India and increased in southern India over the past decade. Trend analysis shows that much of this variability can be explained by changes in irrigation in response to monsoon precipitation.

Akarsh Asoka
Tom Gleeson
Vimal Mishra
Research09 Jan 2017
Nature Geoscience

Volume: 10, P: 109-117
The global volume and distribution of modern groundwater

Groundwater recharged less than 50 years ago is vulnerable to contamination and land-use changes. Data and simulations suggest that up to 6% of continental groundwater is modern—forming the largest component of the active hydrologic cycle.

Tom Gleeson
Kevin M. Befus
M. Bayani Cardenas
Research16 Nov 2015
Nature Geoscience

Volume: 9, P: 161-167
Wedge approach to water stress

Water availability and use are inherently regional concerns. However, a global-scale approach to evaluating strategies to reduce water stress can help maximize mitigation.

Yoshihide Wada
Tom Gleeson
Laurent Esnault
Comments & Opinion28 Aug 2014
Nature Geoscience

Volume: 7, P: 615-617
Author Correction: Global water resources and the role of groundwater in a resilient water future

Bridget R. Scanlon
Sarah Fakhreddine
Chunmiao Zheng
Amendments and Corrections29 Mar 2023
Nature Reviews Earth & Environment

Volume: 4, P: 351
International genome-wide meta-analysis identifies new primary biliary cirrhosis risk loci and targetable pathogenic pathways

Primary biliary cirrhosis is an autoimmune liver disease with poor therapeutic options. Here Cordell et al. a perform meta-analysis of European genome-wide association studies identifying six novel risk loci and a number of potential therapeutic pathways.

Heather J. Cordell
Younghun Han
Katherine A. Siminovitch
ResearchOpen Access22 Sept 2015
Nature Communications

Volume: 6, P: 1-11
Overlooked risks and opportunities in groundwatersheds of the world’s protected areas

Global initiatives to expand protected areas focus on controlling ‘above ground’ impacts such as land use, overlooking the potential human impacts on protected areas through groundwater flow. This study analyses the potential extent of these impacts by mapping groundwatersheds.

Xander Huggins
Tom Gleeson
Andreas Hartmann
Research30 Mar 2023
Nature Sustainability

Volume: 6, P: 855-864
Drought in the Anthropocene

Drought management is inefficient because feedbacks between drought and people are not fully understood. In this human-influenced era, we need to rethink the concept of drought to include the human role in mitigating and enhancing drought.

Anne F. Van Loon
Tom Gleeson
Henny A. J. Van Lanen
Comments & Opinion02 Feb 2016
Nature Geoscience

Volume: 9, P: 89-91
Groundwater sustainability strategies

Aquifers are the primary source of drinking water for up to two billion people. To avoid overexploitation, lengthy renewal periods of some aquifers must be taken into account.

Tom Gleeson
Jonathan VanderSteen
Yangxiao Zhou
Comments & Opinion01 Jun 2010
Nature Geoscience

Volume: 3, P: 378-379
Rethinking groundwater age

It is commonly thought that old groundwater cannot be pumped sustainably, and that recently recharged groundwater is inherently sustainable. We argue that both old and young groundwaters can be used in physically sustainable or unsustainable ways.

Grant Ferguson
Mark O. Cuthbert
Jennifer C. McIntosh
Comments & Opinion01 Sept 2020
Nature Geoscience

Volume: 13, P: 592-594
Environmental flow limits to global groundwater pumping

Estimates for when critical environmental streamflow limits will be reached—with potentially devastating economic and environmental effects—are obtained using a global model that links groundwater pumping with the groundwater flow to rivers.

Inge E. M. de Graaf
Tom Gleeson
Marc F. P. Bierkens
Research02 Oct 2019
Nature

Volume: 574, P: 90-94
Global water resources and the role of groundwater in a resilient water future

Water resources are threatened by human activities and climate variability. This Review discusses trends in water storage and availability and examines ways to enhance water-resource resilience through green and grey solutions.

Bridget R. Scanlon
Sarah Fakhreddine
Chunmiao Zheng
Reviews31 Jan 2023
Nature Reviews Earth & Environment

Volume: 4, P: 87-101
Regional strategies for the accelerating global problem of groundwater depletion

The world's largest freshwater resource is groundwater. A review of our understanding of groundwater depletion suggests that although the problem is global, solutions must be adapted to specific regional requirements at the aquifer scale.

Werner Aeschbach-Hertig
Tom Gleeson
Reviews18 Nov 2012
Nature Geoscience

Volume: 5, P: 853-861
A planetary boundary for green water

The planetary boundaries framework outlines a safe operating space for humanity according to key Earth system dynamics. This Perspective proposes the addition of a green water planetary boundary based on root-zone soil moisture and demonstrates that widespread green water modifications now present increasing risks to Earth system resilience.

Lan Wang-Erlandsson
Arne Tobian
Johan Rockström
Reviews26 Apr 2022
Nature Reviews Earth & Environment

Volume: 3, P: 380-392
Delineating COVID-19 subgroups using routine clinical data identifies distinct in-hospital outcomes

Bojidar Rangelov
Alexandra Young
Mark Radon
ResearchOpen Access20 Jun 2023
Scientific Reports

Volume: 13, P: 1-14
Author Correction: Global karst springs hydrograph dataset for research and management of the world’s fastest-flowing groundwater

Tunde Olarinoye
Tom Gleeson
Andreas Hartmann
Amendments and CorrectionsOpen Access30 Jul 2020
Scientific Data

Volume: 7, P: 1
Global karst springs hydrograph dataset for research and management of the world’s fastest-flowing groundwater

Tunde Olarinoye
Tom Gleeson
Andreas Hartmann
ResearchOpen Access20 Feb 2020
Scientific Data

Volume: 7, P: 1-9
Prostate-specific antigen velocity in a prospective prostate cancer screening study of men with genetic predisposition

Christos Mikropoulos
Christina G Hutten Selkirk
Rosalind A Eeles
ResearchOpen Access04 Jan 2018
British Journal of Cancer

Volume: 118, P: 266-276
Author Correction: Delineating COVID-19 subgroups using routine clinical data identifies distinct in-hospital outcomes

Bojidar Rangelov
Alexandra Young
Mark Radon
Amendments and CorrectionsOpen Access26 Oct 2023
Scientific Reports

Volume: 13, P: 1

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