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Showing 1–2 of 2 results
Advanced filters: Author: Toman Borteçen Clear advanced filters

  • Synthesizing the cellular proteome is demanding and finely regulated. Here, the authors show that mTORC1 cooperates with tRNA wobble modification to promote ribosomal protein synthesis, thus supporting the high translational demands of cell growth.

    • Julia Hermann
    • Toman Borteçen
    • Wilhelm Palm
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-19

  • Analysis of newly synthesized proteins upon perturbation can provide detailed insights into immediate proteome remodeling, which drives cellular responses. Here, the authors report an optimized semi-automated workflow for the quantitative analysis of the newly synthesized proteome.

    • Toman Borteçen
    • Torsten Müller
    • Jeroen Krijgsveld
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-16