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Nature Immunology (2)
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Showing 1–3 of 3 results

Advanced filters: Author: Tomas Castro-Dopico Clear advanced filters

Cross-presentation of dead cell-associated antigens shapes the neoantigenic landscape of tumor immunity

Here the authors show DNGR-1 expressed by cDC1s promotes CD8⁺ T cell priming to cytoskeletal neoantigens from dying tumor cells, thereby shaping cancer immune visibility and tumor evolution through immunoediting.

Kok Haw Jonathan Lim
Oliver Schulz
Caetano Reis e Sousa
ResearchOpen Access02 Jan 2026
Nature Immunology

Volume: 27, P: 72-81
Ulcerative colitis is characterized by a plasmablast-skewed humoral response associated with disease activity

Multi-modal profiling reveals major alterations in colonic B cells in patients with ulcerative colitis, including reduced clonal diversity of plasma cells, and suggests that circulating gut-homing plasmablasts could serve as a biomarker for disease activity.

Mathieu Uzzan
Jerome C. Martin
Saurabh Mehandru
Research21 Feb 2022
Nature Medicine

Volume: 28, P: 766-779
Distinct microbial and immune niches of the human colon

The gut microbiota and their proximate immune cells engage in a dialog of reciprocal regulation. James and colleagues describe how immune cell and microbiotal populations vary along the length of the human colon.

Kylie R. James
Tomas Gomes
Sarah A. Teichmann
Research17 Feb 2020
Nature Immunology

Volume: 21, P: 343-353