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Nature Biomedical Engineering (1)

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Aberrant mechanosensing in injured intervertebral discs as a result of boundary-constraint disruption and residual-strain loss

The loss of residual strains in the intervertebral disc alters the microenvironment and instigates aberrant tissue remodelling and the adoption of atypical cellular phenotypes, promoting disease progression.

Edward D. Bonnevie
Sarah E. Gullbrand
Robert L. Mauck
Research14 Oct 2019
Nature Biomedical Engineering

Volume: 3, P: 998-1008

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Aberrant mechanosensing in injured intervertebral discs as a result of boundary-constraint disruption and residual-strain loss

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