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Showing 1–4 of 4 results

Advanced filters: Author: Toshihide Hamabe-Horiike Clear advanced filters

Fibroblast-specific PRMT5 deficiency suppresses cardiac fibrosis and left ventricular dysfunction in male mice

Epigenetic mechanisms play a key role in cardiac fibrosis associated with heart failure. Here, the authors show that protein arginine methyltransferase 5 (PRMT5), an epigenetic writer, regulates fibrotic gene transcription through histone methylation in mice.

Yasufumi Katanasaka
Harumi Yabe
Tatsuya Morimoto
ResearchOpen Access19 Mar 2024
Nature Communications

Volume: 15, P: 1-13
Evolutionary changes leading to efficient glymphatic circulation in the mammalian brain

The functional consequences of the brain changes during evolution remain unclear. Here, the authors use mathematical modeling and experimental validation to demonstrate a relationship between evolutionary brain changes and glymphatic circulation.

Narufumi Kameya
Itsuki Sakai
Hiroshi Kawasaki
ResearchOpen Access04 Dec 2024
Nature Communications

Volume: 15, P: 1-17
Glial cell type-specific gene expression in the mouse cerebrum using the piggyBac system and in utero electroporation

Toshihide Hamabe-Horiike
Kanji Kawasaki
Hiroshi Kawasaki
ResearchOpen Access01 Mar 2021
Scientific Reports

Volume: 11, P: 1-14
BMP signaling alters aquaporin-4 expression in the mouse cerebral cortex

Kazuya Morita
Naoyuki Matsumoto
Hiroshi Kawasaki
ResearchOpen Access18 May 2021
Scientific Reports

Volume: 11, P: 1-11