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Showing 1–2 of 2 results
Advanced filters: Author: Tove Widén Clear advanced filters

  • Erik Ingelsson and colleagues report a large-scale genome-wide meta-analysis for associations to the extremes of anthropometric traits, including body mass index, height, waist-to-hip ratio and clinical obesity. They identify four loci newly associated with height and seven loci newly associated with clinical obesity and find overlap in the genetic structure and distribution of variants identified for these extremes of the trait distributions and for the general population.

    • Sonja I Berndt
    • Stefan Gustafsson
    • Erik Ingelsson
    Research
    Nature Genetics
    Volume: 45, P: 501-512

  • Mazurkewich et al. report a phylogenetic, biochemical, and structural investigation of GH71 enzymes from Aspergillus nidulans, revealing distinct activities on α-1,3 glucooligosaccharides and roles in fungal cell wall remodeling. Their work uncovers the first GH71 structure with bound ligands, identifies a crucial DxxE catalytic dyad, and highlights the functional diversity of this poorly understood enzyme family.

    • Scott Mazurkewich
    • Tove Widén
    • Johan Larsbrink
    ResearchOpen Access
    Communications Biology
    Volume: 8, P: 1-13