Nguyen et al. conduct a randomized, double-blind, controlled clinical trial evaluating multi-strain Bacillus spore probiotics for treating functional constipation in preschool children. The probiotics significantly reduce constipation, anorexia, and underweight risk and improve immune markers and gut microbiota composition after 7–28 days of use.
- Hanh Thi Luong Nguyen
- Hang Thi Hoang
- Anh Thi Van Nguyen