Nature Search

Randomized trial of smartphone application and bed sensor for atrial fibrillation detection in high-risk patients

Joonas Lehto
Joel Nuotio
Tuomas O. Kiviniemi
ResearchOpen Access03 Feb 2026
Scientific Reports

P: 1-12
Red blood cell transfusion induces abnormal HIF-1α response to cytokine storm after adult cardiac surgery

Emma Viikinkoski
Juho Jalkanen
Tuomas O. Kiviniemi
ResearchOpen Access15 Nov 2021
Scientific Reports

Volume: 11, P: 1-9
Chromosome Xq23 is associated with lower atherogenic lipid concentrations and favorable cardiometabolic indices

The influence of X chromosome genetic variation on blood lipids and coronary heart disease (CHD) is not well understood. Here, the authors analyse X chromosome sequencing data across 65,322 multi-ancestry individuals, identifying associations of the Xq23 locus with lipid changes and reduced risk of CHD and diabetes mellitus.

Pradeep Natarajan
Akhil Pampana
Gina M. Peloso
ResearchOpen Access12 Apr 2021
Nature Communications

Volume: 12, P: 1-14
Inherited myeloproliferative neoplasm risk affects haematopoietic stem cells

A genome-wide association study identifies 17 genetic loci that are associated with the risk of myeloproliferative neoplasms (MPNs), and shows that the modulation of haematopoietic stem cell function drives MPN risk.

Erik L. Bao
Satish K. Nandakumar
Vijay G. Sankaran
Research14 Oct 2020
Nature

Volume: 586, P: 769-775
Genome-wide meta-analysis identifies 127 open-angle glaucoma loci with consistent effect across ancestries

Primary open-angle glaucoma (POAG) is highly heritable, yet not well understood from a genetic perspective. Here, the authors perform a meta-analysis of genome-wide association studies in 34,179 POAG cases, identifying 44 previously unreported risk loci and mapping effects across multiple ethnicities.

Puya Gharahkhani
Eric Jorgenson
Janey L. Wiggs
ResearchOpen Access24 Feb 2021
Nature Communications

Volume: 12, P: 1-16
Genetic architecture of human plasma lipidome and its link to cardiovascular disease

Cardiovascular diseases (CVD) are associated with plasma lipid levels. Here, Tabassum et al. perform genome-wide association studies for lipidomic profiles with 141 (non-standard) lipid species which highlights shared genetic loci with CVD and that traditional lipids have low genetic correlation with other lipids.

Rubina Tabassum
Joel T. Rämö
Samuli Ripatti
ResearchOpen Access24 Sept 2019
Nature Communications

Volume: 10, P: 1-14
Multiclass Classifier based Cardiovascular Condition Detection Using Smartphone Mechanocardiography

Zuhair Iftikhar
Olli Lahdenoja
Mikko Pänkäälä
ResearchOpen Access19 Jun 2018
Scientific Reports

Volume: 8, P: 1-14
Differential circulating cytokine profiles in acute coronary syndrome versus stable coronary artery disease

Eveliina Maaniitty
Juho Jalkanen
Tuomas Kiviniemi
ResearchOpen Access27 Jul 2024
Scientific Reports

Volume: 14, P: 1-10
The glymphatic system: implications for drugs for central nervous system diseases

Evidence for a fluid clearance pathway in the central nervous system known as the glymphatic system has grown in the past decade. Nedergaard and colleagues overview the evidence for the glymphatic system and its role in disease, and discuss opportunities to harness the glymphatic system therapeutically; for example, by improving the effectiveness of intrathecally delivered drugs.

Terhi J. Lohela
Tuomas O. Lilius
Maiken Nedergaard
Reviews10 Aug 2022
Nature Reviews Drug Discovery

Volume: 21, P: 763-779
Polygenic and clinical risk scores and their impact on age at onset and prediction of cardiometabolic diseases and common cancers

In a large and prospective cohort, higher polygenic risk is associated with higher risk and earlier age of onset for cardiometabolic disorders and cancer, and has added value to clinical risk scores in clinical disease prediction.

Nina Mars
Jukka T. Koskela
Samuli Ripatti
Research07 Apr 2020
Nature Medicine

Volume: 26, P: 549-557
An expanded analysis framework for multivariate GWAS connects inflammatory biomarkers to functional variants and disease

Sanni E. Ruotsalainen
Juulia J. Partanen
Jukka Koskela
Research27 Oct 2020
European Journal of Human Genetics

Volume: 29, P: 309-324
Clinical assessment of a non-invasive wearable MEMS pressure sensor array for monitoring of arterial pulse waveform, heart rate and detection of atrial fibrillation

Matti Kaisti
Tuukka Panula
Mikko Pänkäälä
ResearchOpen Access14 May 2019
npj Digital Medicine

Volume: 2, P: 1-10

Search

Filter By:

Search

Quick links