Genome-wide association studies (GWAS) have identified over 200 genetic risk loci for breast cancer, but the target genes in these loci remain largely unknown. Here, the authors conduct multi-ancestry transcriptome-wide association studies to discover potential breast cancer susceptibility genes, which are further explored with single-cell sequencing and in vitro experiments.
- Jie Ping
- Guochong Jia
- Wei Zheng
