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Showing 1–5 of 5 results

Advanced filters: Author: Tyler A. Sisley Clear advanced filters

Author Correction: Efficient C•G-to-G•C base editors developed using CRISPRi screens, target-library analysis, and machine learning

Luke W. Koblan
Mandana Arbab
David R. Liu
Amendments and Corrections18 Oct 2023
Nature Biotechnology

Volume: 41, P: 1655
FacZ is a GpsB-interacting protein that prevents aberrant division-site placement in Staphylococcus aureus

FacZ is a division site placement factor that antagonizes the cell division protein GpsB in Staphylococcus aureus.

Thomas M. Bartlett
Tyler A. Sisley
Thomas G. Bernhardt
ResearchOpen Access05 Mar 2024
Nature Microbiology

Volume: 9, P: 801-813
Auxiliary interfaces support the evolution of specific toxin–antitoxin pairing

Structural characterization of three paralogous toxin–antitoxin complexes illuminates how each antitoxin specifically targets its cognate toxin, including auxiliary neutralization interfaces that confer evolvability while preventing loss of activity.

Grzegorz J. Grabe
Rachel T. Giorgio
Sophie Helaine
Research23 Sept 2021
Nature Chemical Biology

Volume: 17, P: 1296-1304
Allosteric activation of cell wall synthesis during bacterial growth

Coordination of cell wall assembly is critical for bacterial morphology and survival. Here, the authors show that activation of cell wall synthesis by the Rod complex is regulated by the structural dynamics of RodA-PBP2.

Irina Shlosman
Elayne M. Fivenson
Joseph J. Loparo
ResearchOpen Access10 Jun 2023
Nature Communications

Volume: 14, P: 1-14
Efficient C•G-to-G•C base editors developed using CRISPRi screens, target-library analysis, and machine learning

Efficiency of transversion base editing is increased by matching a set of base editors to target sequences.

Luke W. Koblan
Mandana Arbab
David R. Liu
Research28 Jun 2021
Nature Biotechnology

Volume: 39, P: 1414-1425