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Showing 1–6 of 6 results
Advanced filters: Author: Tyler J. Lefevre Clear advanced filters

  • UDP-glucuronic acid is a component of the extracellular matrix. Here, the authors report biallelic variants in the gene encoding UDP-Glucose 6-Dehydrogenase (UGDH) in individuals affected by developmental epileptic encephalopathies that impair UGDH stability, oligomerization, or enzymatic activity in vitro.

    • Holger Hengel
    • Célia Bosso-Lefèvre
    • Bruno Reversade
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-16

  • In this immunological ancillary study of the PREVAC trial, the authors show that approved Ebola virus vaccines induce memory T-cell responses that persist during the five year follow-up after initial vaccination.

    • Aurélie Wiedemann
    • Edouard Lhomme
    • Huanying Zhou
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-15

  • Evidence for the presence of Homo during the Middle Pleistocene is limited in continental Southeast Asia. Here, the authors report a hominin molar from Tam Ngu Hao 2 (Cobra Cave), dated to 164–131 kyr. They use morphological and paleoproteomic analysis to show that it likely belonged to a female Denisovan.

    • Fabrice Demeter
    • Clément Zanolli
    • Laura Shackelford
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-17

  • In an inter-laboratory study, the authors compare the accuracy and performance of three optical density calibration protocols (colloidal silica, serial dilution of silica microspheres, and colony-forming unit (CFU) assay). They demonstrate that serial dilution of silica microspheres is the best of these tested protocols, allowing precise and robust calibration that is easily assessed for quality control and can also evaluate the effective linear range of an instrument.

    • Jacob Beal
    • Natalie G. Farny
    • Jiajie Zhou
    ResearchOpen Access
    Communications Biology
    Volume: 3, P: 1-29