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Advanced filters: Author: Tyler S. Halpin-Healy Clear advanced filters

Publisher Correction: Structural basis of DNA targeting by a transposon-encoded CRISPR–Cas system

Tyler S. Halpin-Healy
Sanne E. Klompe
Israel S. Fernández
Amendments and Corrections26 Aug 2020
Nature

Volume: 585, P: E12
Transposon-encoded CRISPR–Cas systems direct RNA-guided DNA integration

A programmable transposase integrates donor DNA at user-defined genomic target sites with high fidelity, revealing a new approach for genetic engineering that obviates the need for DNA double-strand breaks and homologous recombination.

Sanne E. Klompe
Phuc L. H. Vo
Samuel H. Sternberg
Research12 Jun 2019
Nature

Volume: 571, P: 219-225
Targeted DNA integration in human cells without double-strand breaks using CRISPR-associated transposases

Large DNA sequences are integrated into human cells using RNA-guided CRISPR-associated transposases.

George D. Lampe
Rebeca T. King
Samuel H. Sternberg
Research29 Mar 2023
Nature Biotechnology

Volume: 42, P: 87-98
Structural basis of DNA targeting by a transposon-encoded CRISPR–Cas system

Cryo-electron microscopy structures of the TniQ–Cascade complex encoded by the Vibrio cholerae Tn6677 transposon reveal the mechanistic basis of the functional association of CRISPR- and transposon-associated machineries.

Tyler S. Halpin-Healy
Sanne E. Klompe
Israel S. Fernández
Research18 Dec 2019
Nature

Volume: 577, P: 271-274