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Showing 1–2 of 2 results
Advanced filters: Author: Tzu-Han Weng Clear advanced filters

  • Glycogenin initiates glycogen synthesis, but its two human isoforms may do more than expected. Here, Weng et al. reveal that GYG2, despite low enzyme activity, drives glycogen particle assembly, uncovering a new layer of metabolic control.

    • Tzu-Han Weng
    • Yu-Chung Pien
    • Su-Yi Tsai
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-21

  • Vinca alkaloids, tubulin-binding agents that impair microtubule growth, are widely used in cancer treatment. Here, the authors show that resistance to these drugs is due to Hepatoma up-regulated protein (HURP) competitively binding to the same site on tubulin, countering the drug’s effects.

    • Athira Saju
    • Po-Pang Chen
    • Kuo-Chiang Hsia
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-20