Nature Search

Mapping the genetic landscape across 14 psychiatric disorders

Genomic analyses applied to 14 childhood- and adult-onset psychiatric disorders identifies five underlying genomic factors that explain the majority of the genetic variance of the individual disorders.

Andrew D. Grotzinger
Josefin Werme
Jordan W. Smoller
ResearchOpen Access10 Dec 2025
Nature

Volume: 649, P: 406-415
The effect of quality and amount of dietary fat on the susceptibility of low density lipoprotein to oxidation in subjects with impaired glucose tolerance

US Schwab
ES Sarkkinen
MIJ Uusitupa
Research26 May 1998
European Journal of Clinical Nutrition

Volume: 52, P: 452-458
A multimodal whole-body atlas

Researchers have registered a gene expression atlas to a whole-body EM volume of a marine bristle worm.

Rita Strack
Research Highlights04 Oct 2021
Nature Methods

Volume: 18, P: 1145
Tracking the Trump transition, agency by agency

Nature's list of the key issues and appointments facing US government science agencies.

Jeff Tollefson
Sara Reardon
Heidi Ledford
News30 Nov 2016
Nature
Neuroblastoma plasticity during metastatic progression stems from the dynamics of an early sympathetic transcriptomic trajectory

The roots of neuroblastoma plasticity and heterogeneity remain poorly understood. Here, the authors characterise the transcriptional states of neuroblastoma cells and their changes throughout development using avian embryo models, single-cell RNA-sequencing, and patient samples; they find transcriptomic changes related to early sympatho-adrenal development.

Benjamin Villalard
Arjan Boltjes
Valérie Castellani
ResearchOpen Access06 Nov 2024
Nature Communications

Volume: 15, P: 1-19
Vibrio pectenicida strain FHCF-3 is a causative agent of sea star wasting disease

The causative agent of sea star wasting disease has been elusive. This study used genetic datasets and experimental exposures to demonstrate that a strain of the bacterium Vibrio pectenicida caused disease and mortality in sea stars.

Melanie B. Prentice
Grace A. Crandall
Alyssa-Lois M. Gehman
Research04 Aug 2025
Nature Ecology & Evolution

Volume: 9, P: 1739-1751
Cobalt in ferromanganese crusts as a monitor of hydrothermal discharge on the Pacific sea floor

F. T. Manheim
C. M. Lane-Bostwick
Research01 Sept 1988
Nature

Volume: 335, P: 59-62
Understanding variability in time spent in selected locations for 7–12-year old children

Jianping Xue
Thomas McCurdy
Hâluk Özkaynak
Research13 May 2004
Journal of Exposure Science & Environmental Epidemiology

Volume: 14, P: 222-233
Near to the edge of an ice sheet

Steven W. Hostetler
News & Views30 Jan 1997
Nature

Volume: 385, P: 393-394
New Structures from the Dehydrogenation of Model Compounds related to Lignin

JOHN C. PEW
WILLIAM J. CONNORS
Research05 Aug 1967
Nature

Volume: 215, P: 623-625
Complement genes contribute sex-biased vulnerability in diverse disorders

Sexual dimorphism in genetic vulnerability to schizophrenia, systemic lupus erythematosus and Sjögren’s syndrome is linked to differential protein abundance from alleles of complement component 4.

Nolan Kamitaki
Aswin Sekar
Steven A. McCarroll
Research11 May 2020
Nature

Volume: 582, P: 577-581
Genetic influences on schizophrenia and subcortical brain volumes: large-scale proof of concept

The authors defined a roadmap for investigating the genetic covariance between structural or functional brain phenotypes and risk for psychiatric disorders. Their proof-of-concept study using the largest available common variant data sets for schizophrenia and volumes of several (mainly subcortical) brain structures did not find evidence of genetic overlap.

Barbara Franke
Jason L Stein
Patrick F Sullivan
Research01 Feb 2016
Nature Neuroscience

Volume: 19, P: 420-431
Enhancing post-kidney transplant prognostication: an interpretable machine learning approach for longitudinal outcome prediction

Bowen Fan
Manuel Schürch
Patrick Yerly
ResearchOpen Access18 Nov 2025
npj Digital Medicine

Volume: 8, P: 1-11
Using human activity data in exposure models: Analysis of discriminating factors

Thomas Mccurdy
Stephen E Graham
Research15 Jul 2003
Journal of Exposure Science & Environmental Epidemiology

Volume: 13, P: 294-317
Targeting the sphingosine-1-phosphate axis in cancer, inflammation and beyond

Sphingosine-1-phosphate (S1P) has a key role in the control of immune cell trafficking and is involved in disorders including cancer and inflammatory diseases. Here, Spiegel and colleagues discuss the ways in which S1P could be therapeutically targeted and highlight recent data from preclinical studies and clinical trials.

Gregory T. Kunkel
Michael Maceyka
Sarah Spiegel
Reviews19 Aug 2013
Nature Reviews Drug Discovery

Volume: 12, P: 688-702
Developing meaningful cohorts for human exposure models

Stephen E Graham
Thomas McCurdy
Research02 Jan 2004
Journal of Exposure Science & Environmental Epidemiology

Volume: 14, P: 23-43
Multimedia measurements and activity patterns in an observational pilot study of nine young children

Nicolle S Tulve
Peter P Egeghy
Aaron Hilliard
Research12 Sept 2007
Journal of Exposure Science & Environmental Epidemiology

Volume: 18, P: 31-44
The impact of the leucine 7 to proline 7 polymorphism of the neuropeptide Y gene on postprandial lipemia and on the response of serum total and lipoprotein lipids to a reduced fat diet

US Schwab
JJ Ågren
MJ Savolainen
Research20 Feb 2002
European Journal of Clinical Nutrition

Volume: 56, P: 149-156
Statistical properties of longitudinal time-activity data for use in human exposure modeling

Kristin Isaacs
Thomas McCurdy
Daniel Vallero
Research10 Oct 2012
Journal of Exposure Science & Environmental Epidemiology

Volume: 23, P: 328-336
Acute lymphoblastic leukaemia: a model for the pharmacogenomics of cancer therapy

Germline polymorphisms and gene-expression profiles in acute lymphoblastic leukaemia (ALL) cells are emerging as useful clinical diagnostics for this disease. Lessons learnt from development of polygenic models for ALL might inform the optimization of treatment for other cancers.

Meyling H. Cheok
William E. Evans
Reviews01 Feb 2006
Nature Reviews Cancer

Volume: 6, P: 117-129

Search

Mapping the genetic landscape across 14 psychiatric disorders

The effect of quality and amount of dietary fat on the susceptibility of low density lipoprotein to oxidation in subjects with impaired glucose tolerance

A multimodal whole-body atlas

Tracking the Trump transition, agency by agency

Neuroblastoma plasticity during metastatic progression stems from the dynamics of an early sympathetic transcriptomic trajectory

Vibrio pectenicida strain FHCF-3 is a causative agent of sea star wasting disease

Cobalt in ferromanganese crusts as a monitor of hydrothermal discharge on the Pacific sea floor

Understanding variability in time spent in selected locations for 7–12-year old children

Near to the edge of an ice sheet

New Structures from the Dehydrogenation of Model Compounds related to Lignin

Complement genes contribute sex-biased vulnerability in diverse disorders

Genetic influences on schizophrenia and subcortical brain volumes: large-scale proof of concept

Enhancing post-kidney transplant prognostication: an interpretable machine learning approach for longitudinal outcome prediction

Using human activity data in exposure models: Analysis of discriminating factors

Targeting the sphingosine-1-phosphate axis in cancer, inflammation and beyond

Developing meaningful cohorts for human exposure models

Multimedia measurements and activity patterns in an observational pilot study of nine young children

The impact of the leucine 7 to proline 7 polymorphism of the neuropeptide Y gene on postprandial lipemia and on the response of serum total and lipoprotein lipids to a reduced fat diet

Statistical properties of longitudinal time-activity data for use in human exposure modeling

Acute lymphoblastic leukaemia: a model for the pharmacogenomics of cancer therapy

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