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Nature Structural & Molecular Biology (3)
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Showing 1–11 of 11 results

Advanced filters: Author: Ulrich Baxa Clear advanced filters

Erratum: Early steps in primary cilium assembly require EHD1/EHD3-dependent ciliary vesicle formation

Quanlong Lu
Christine Insinna
Christopher J. Westlake
Amendments and Corrections27 Mar 2015
Nature Cell Biology

Volume: 17, P: 531
Erratum: Platelet-derived growth factor-α receptor is the cellular receptor for human cytomegalovirus gHgLgO trimer

Anna Kabanova
Jessica Marcandalli
Laurent Perez
Amendments and Corrections20 Jun 2016
Nature Microbiology

Volume: 1, P: 1
Author Correction: Mosaic nanoparticle display of diverse influenza virus hemagglutinins elicits broad B cell responses

Masaru Kanekiyo
M. Gordon Joyce
Barney S. Graham
Amendments and Corrections12 Apr 2019
Nature Immunology

Volume: 20, P: 765
Structures of HIV-1 Env V1V2 with broadly neutralizing antibodies reveal commonalities that enable vaccine design

Crystal structures of HIV-1 Env V1V2 in complex with human broadly neutralizing antibodies and ontogeny analyses allow the engineering of Env trimers that are recognized by ancestor and intermediate antibody forms.

Jason Gorman
Cinque Soto
Peter D Kwong
Research21 Dec 2015
Nature Structural & Molecular Biology

Volume: 23, P: 81-90
Mosaic nanoparticle display of diverse influenza virus hemagglutinins elicits broad B cell responses

Antigenic variation of influenza A viruses necessitates the annual reformulation of vaccines. Kanekiyo et al. develop a mosaic nanoparticle vaccine against influenza virus that is able to elicit neutralizing antibodies that span nearly 100 years of variation of influenza A virus.

Masaru Kanekiyo
M. Gordon Joyce
Barney S. Graham
Research11 Feb 2019
Nature Immunology

Volume: 20, P: 362-372
Crystal structure, conformational fixation and entry-related interactions of mature ligand-free HIV-1 Env

The structure of the ligand-free HIV-1–Env trimer allows conformational fixation of Env and generation of an antigen that binds CD4 with high affinity and is recognized by broadly neutralizing antibodies but not poorly neutralizing ones.

Young Do Kwon
Marie Pancera
Peter D Kwong
Research22 Jun 2015
Nature Structural & Molecular Biology

Volume: 22, P: 522-531
Iterative structure-based improvement of a fusion-glycoprotein vaccine against RSV

An interactive structure-based approach was used to improve a vaccine antigen against respiratory syncytium virus (RSV), thus leading to immunogens with higher stability that elicit higher neutralizing titers in mice.

M Gordon Joyce
Baoshan Zhang
Peter D Kwong
Research01 Aug 2016
Nature Structural & Molecular Biology

Volume: 23, P: 811-820
Early steps in primary cilium assembly require EHD1/EHD3-dependent ciliary vesicle formation

Westlake and colleagues discover that membrane shaping EHD proteins participate in ciliogenesis by taking part in ciliary vesicle formation and transition zone protein recruitment.

Quanlong Lu
Christine Insinna
Christopher J. Westlake
Research16 Feb 2015
Nature Cell Biology

Volume: 17, P: 228-240
Platelet-derived growth factor-α receptor is the cellular receptor for human cytomegalovirus gHgLgO trimer

The human cytomegalovirus (HCMV) gHgLgO trimer binds with high affinity through the gO subunit to platelet-derived growth factor-α receptor (PDGFRα), which is expressed on fibroblasts but not on epithelial cells.

Anna Kabanova
Jessica Marcandalli
Laurent Perez
Research06 Jun 2016
Nature Microbiology

Volume: 1, P: 1-8
Structural basis for early-onset neurological disorders caused by mutations in human selenocysteine synthase

Anupama K. Puppala
Rachel L. French
Miljan Simonović
ResearchOpen Access31 Aug 2016
Scientific Reports

Volume: 6, P: 1-12
Protection of calves by a prefusion-stabilized bovine RSV F vaccine

Baoshan Zhang
Lei Chen
Peter D. Kwong
ResearchOpen Access08 Mar 2017
npj Vaccines

Volume: 2, P: 1-11