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Showing 1–5 of 5 results

Advanced filters: Author: V. Martemyanov Clear advanced filters

Ultra-large virtual screening unveils potent agonists of the neuromodulatory orphan receptor GPR139

In this work, a library of several hundred million compounds was computationally docked to a cryoEM structure of the orphan G protein-coupled receptor GPR139, leading to the discovery of a potent agonist with in vivo effects and insights into GPR139 signalling.

Israel Cabeza de Vaca
Boris Trapkov
Jens Carlsson
ResearchOpen Access09 Dec 2025
Nature Communications

Volume: 17, P: 1-16
Adaptive capacity of Asian populations of Lymantria dispar to non preferred plants during northward expansion

E. L. Arzhanova
S. V. Pavlushin
V. V. Martemyanov
ResearchOpen Access16 Jan 2026
Scientific Reports

Volume: 16, P: 1-12
Virulence and genome analysis of baculovirus isolates from different Lymantria dispar populations

Y. Akhanaev
S. Pavlushin
V. Martemyanov
ResearchOpen Access04 Aug 2025
Scientific Reports

Volume: 15, P: 1-10
R7BP Complexes With RGS9-2 and RGS7 in the Striatum Differentially Control Motor Learning and Locomotor Responses to Cocaine

Garret R Anderson
Yan Cao
Kirill A Martemyanov
Research30 Dec 2009
Neuropsychopharmacology

Volume: 35, P: 1040-1050
A neurodevelopmental disorder mutation locks G proteins in the transitory pre-activated state

Many neurotransmitters act on receptors coupled to GTP-binding G proteins. Here authors report the structure and activity of a mutant that locks the nucleotide-free and receptor-bound state of the G protein, leading to a rare neurological disorder.

Kevin M. Knight
Brian E. Krumm
Henrik G. Dohlman
ResearchOpen Access05 Aug 2024
Nature Communications

Volume: 15, P: 1-18