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Showing 1–4 of 4 results
Advanced filters: Author: V. O. Chagin Clear advanced filters

  • DNA replication in higher eukaryotes is a complex process occurring in a complex genome environment. Here the authors present a model of DNA replication that incorporates random loop chromatin folding and domino-like fork progression reproducing the spatial and temporal characteristics of S-phase.

    • D. Löb
    • N. Lengert
    • B. Drossel
    ResearchOpen Access
    Nature Communications
    Volume: 7, P: 1-11

  • Neural crest cells differentiate into skeletogenic mesenchyme and neuro-glial lineages, thereby contributing to craniofacial formation. Here, single-cell analysis of cranial neural crest shows that specific rRNA modification and ribosome assembly factors contribute to skeletogenic fate. Their disruption causes craniofacial defects, while high levels in neuroblastoma predict poor survival.

    • Irina Poverennaya
    • Aliia Murtazina
    • Igor Adameyko
    ResearchOpen Access
    Nature Communications
    Volume: 17, P: 1-28

  • Clonal genetic tracing is used to demonstrate that, in mice, longitudinal bone growth during fetal and neonatal periods relies on the gradual consumption of chondroprogenitors, whereas in adults, a stem cell niche is formed allowing renewing of chondroprogenitors and leading to formation of large, stable monoclonal columns of chondrocytes.

    • Phillip T. Newton
    • Lei Li
    • Andrei S. Chagin
    Research
    Nature
    Volume: 567, P: 234-238