Purines control intracellular energy homeostasis and nucleotide synthesis, and act as signaling molecules. Here, the authors combine structural and sequence information to define a purine-binding motif that is present in sensor domains of thousands of bacterial receptors that modulate motility, gene expression, metabolism, and second-messenger turnover.
- Elizabet Monteagudo-Cascales
- Vadim M. Gumerov
- Tino Krell
