Advanced search

Filter By:

Journal Check one or more journals to show results from those journals only.

Choose more journals

Article type Check one or more article types to show results from those article types only.
Subject Check one or more subjects to show results from those subjects only.
Date Choose a date option to show results from those dates only.

Custom date range

Clear all filters
Sort by:
Showing 1–2 of 2 results
Advanced filters: Author: Vaggelis Harokopos Clear advanced filters

  • The activation and accumulation of lung fibroblasts resulting in aberrant deposition of extracellular matrix components is a pathogenic hallmark of idiopathic pulmonary fibrosis. Here, the authors show that the formation of podosomes in lung fibroblasts stimulates extracellular matrix invasion in a mouse model of the disease, suggesting that pharmacological targeting of podosome formation or organization might be a therapeutic option.

    • Ilianna Barbayianni
    • Paraskevi Kanellopoulou
    • Vassilis Aidinis
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-20

  • Malignant pleural effusion (MPE) is a lethal condition associated with various cancers. Here, the authors show that cancer cells withKRASmutations promote MPE by recruiting myeloid cells via CCL2 signalling and that pharmaceutical targeting of KRAS results in reduced MPE incidence and volume in mouse models.

    • Theodora Agalioti
    • Anastasios D. Giannou
    • Georgios T. Stathopoulos
    ResearchOpen Access
    Nature Communications
    Volume: 8, P: 1-15