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Showing 1–3 of 3 results
Advanced filters: Author: Vaithish Velazhahan Clear advanced filters

  • Blush regularization makes use of a neural network pre-trained on a diverse set of high-resolution cryo-EM half-maps to improve image alignment, effectively lowering the size barrier, during cryo-EM structure determination.

    • Dari Kimanius
    • Kiarash Jamali
    • Sjors H. W. Scheres
    ResearchOpen Access
    Nature Methods
    Volume: 21, P: 1216-1221

  • Cryo-electron microscopy structures of ligand-free, agonist-bound and antagonist-bound Ste2 show that this class D1 G protein-coupled receptor has a distinct mechanism of activation compared with other receptor classes.

    • Vaithish Velazhahan
    • Ning Ma
    • Christopher G. Tate
    ResearchOpen Access
    Nature
    Volume: 603, P: 743-748

  • A cryo-electron microscopy structure of the yeast pheromone receptor Ste2, a class D G-protein-coupled receptor, in its active state reveals that Ste2 is a homodimer that couples to two G proteins.

    • Vaithish Velazhahan
    • Ning Ma
    • Christopher G. Tate
    Research
    Nature
    Volume: 589, P: 148-153