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Showing 1–2 of 2 results
Advanced filters: Author: Valentin Bon-Baret Clear advanced filters

  • Kim Valette et al. perform a genomic study on asthma integrating genome-wide association study, functional mapping using lung and blood transcriptome-wide profiles, as well as Mendelian randomization. They show candidate causal genes expressed in lung and blood tissues that are putative therapeutic targets for asthma.

    • Kim Valette
    • Zhonglin Li
    • Yohan Bossé
    ResearchOpen Access
    Communications Biology
    Volume: 4, P: 1-15

  • Arnaud Chignon et al. present an integrated analysis of single-cell expression data from blood and genome-wide studies to identify expressed genes (eGenes) associated with human lifespan. The 125 eGenes identified are enriched for cardiometabolic traits and disorders and 16 are causally related to lifespan, as shown by Mendelian Randomization analysis.

    • Arnaud Chignon
    • Valentin Bon-Baret
    • Patrick Mathieu
    ResearchOpen Access
    Communications Biology
    Volume: 3, P: 1-15