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Advanced filters: Author: Valentin F. Reichle Clear advanced filters

  • Bacterial tRNA is modified by thiolation of nucleosides. Here the authors identify 2-methylthiocytidine in bacterial tRNA using nucleic acid isotope labeling coupled mass spectrometry. Exposure to methylating agents converts 2-thiocytidine to 2-methylthiocytidine, which is repaired by demethylase AlkB in vivo.

    • Valentin F. Reichle
    • Dimitar P. Petrov
    • Stefanie Kellner
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-11