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Showing 1–3 of 3 results
Advanced filters: Author: Valeria Lulla Clear advanced filters

  • Astroviruses are common human pathogens and their genomes contain three known protein-coding genes. Here, Lulla et al. report a fourth, previously overlooked gene encoding protein XP which has a viroporin-like activity that is important for efficient production and/or release of virus particles.

    • Valeria Lulla
    • Andrew E. Firth
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-15

  • Here the authors identify upstream open reading frames (uORFs), uORF1 and uORF2 in the Asian/American lineage and African uORF in the African lineage of Zika viruses, and show that uORF1 affects vimentin filaments and that the identified uORFs affect virus replication in neural cells.

    • Charlotte Lefèvre
    • Georgia M. Cook
    • Nerea Irigoyen
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-19