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Showing 1–4 of 4 results
Advanced filters: Author: Valeria Manriquez Clear advanced filters

  • The human pathogen Neisseria meningitidis colonizes blood vessels and causes vascular damage, despite a neutrophil-rich inflammatory infiltrate. Here, Manriquez et al. use a humanized mouse model to show that pathogen colonization of capillaries and arterioles creates an intravascular niche that precludes an effective action of neutrophils.

    • Valeria Manriquez
    • Pierre Nivoit
    • Guillaume Duménil
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-15

  • Atypical teratoid rhabdoid tumors (ATRT) are divided into three molecular subgroups, which could have different lineages of origin. Here, the authors use tumour imaging, multi-omics and genetically engineered mouse models to determine the anatomical region and cell lineage of origin of ATRT subtypes.

    • María-Jesús Lobón-Iglesias
    • Mamy Andrianteranagna
    • Franck Bourdeaut
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-21

  • The molecular mechanisms involved in the development of SMARCB1-deficient renal medullary carcinomas (RMCs) remain to be characterised. Here, the authors integrated RMC omics data to show that ferroptosis resistance contributes to transformation of renal thick ascending limb cells into several RMC cell states.

    • Bujamin H. Vokshi
    • Guillaume Davidson
    • Gabriel G. Malouf
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-19

  • Meningococci remodel the plasma membrane of host cells during infection. Here, Charles-Orszag et al. show that plasma membrane remodeling occurs independently of F-actin, along meningococcal type IV pili fibers, by a physical mechanism that they term ‘one-dimensional’ membrane wetting.

    • Arthur Charles-Orszag
    • Feng-Ching Tsai
    • Guillaume Duménil
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-14