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Showing 1–7 of 7 results

Advanced filters: Author: Vanesa Muncan Clear advanced filters

Blimp1 regulates the transition of neonatal to adult intestinal epithelium

Many mammals are born with an immature intestinal epithelium, which adapts to a changing diet during the weaning period. Muncanet al. show that the transcriptional repressor Blimp1is expressed in the intestine of mice at birth, and that expression is lost at the transition to the weaning stage.

Vanesa Muncan
Jarom Heijmans
Gijs R. van den Brink
ResearchOpen Access30 Aug 2011
Nature Communications

Volume: 2, P: 1-9
Myc deletion rescues Apc deficiency in the small intestine

Deregulation of the Wnt signalling pathway has been implicated in the development of cancer, including colorectal tumours. This paper shows that regulation of the transcription factor c-Myc is the most critical target for Wnt signalling in the early stages of intestinal neoplasias.

Owen J. Sansom
Valerie S. Meniel
Alan R. Clarke
Research21 Mar 2007
Nature

Volume: 446, P: 676-679
Dichotomal effect of space flight-associated microgravity on stress-activated protein kinases in innate immunity

Auke P. Verhaar
Elmer Hoekstra
Maikel P. Peppelenbosch
ResearchOpen Access27 Jun 2014
Scientific Reports

Volume: 4, P: 1-5
Epithelial argininosuccinate synthetase is dispensable for intestinal regeneration and tumorigenesis

Jonathan H. M. van der Meer
Ruben J. de Boer
Vanesa Muncan
ResearchOpen Access01 Oct 2021
Cell Death & Disease

Volume: 12, P: 1-13
Endoplasmic reticulum stress regulates the intestinal stem cell state through CtBP2

Bartolomeus J. Meijer
Wouter L. Smit
Jarom Heijmans
ResearchOpen Access10 May 2021
Scientific Reports

Volume: 11, P: 1-15
Epithelium-derived Indian Hedgehog restricts stromal expression of ErbB family members that drive colonic tumor cell proliferation

Florien Westendorp
Olga N. Karpus
Gijs R. van den Brink
Research21 Jan 2021
Oncogene

Volume: 40, P: 1628-1643
Expression of UPR effector proteins ATF6 and XBP1 reduce colorectal cancer cell proliferation and stemness by activating PERK signaling

Claudia N. Spaan
Wouter L. Smit
Jarom Heijmans
ResearchOpen Access21 Jun 2019
Cell Death & Disease

Volume: 10, P: 1-10