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Showing 1–2 of 2 results
Advanced filters: Author: Vasiliya Kril Clear advanced filters

  • The role of alphavirus nsP3 protein is not entirely clear. Here, through structural analysis the authors show that CHIKV nsP3 polymerizes to form tubular scaffolds in both replication complexes and alpha-granules and that these scaffolds are important for virus RNA synthesis and infectivity.

    • Vasiliya Kril
    • Michael Hons
    • Juan Reguera
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-16

  • FHL1 is a key factor expressed by humans and mice that is required for chikungunya virus infection and is therefore a promising target for the development of therapies against chikungunya virus.

    • Laurent Meertens
    • Mohamed Lamine Hafirassou
    • Ali Amara
    Research
    Nature
    Volume: 574, P: 259-263