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Showing 1–7 of 7 results

Advanced filters: Author: Verena Passerini Clear advanced filters

The presence of extra chromosomes leads to genomic instability

One of the hallmarks of cancer cells is aneuploidy, however the molecular effects are poorly understood. Here the authors show that trisomic and tetrasomic cells display increased genomic instability and reduced levels of the helicase MCM2-7.

Verena Passerini
Efrat Ozeri-Galai
Zuzana Storchová
ResearchOpen Access15 Feb 2016
Nature Communications

Volume: 7, P: 1-12
Loss of CREBBP and KMT2D cooperate to accelerate lymphomagenesis and shape the lymphoma immune microenvironment

CREBBP and KMT2D mutations frequently co-occur in B cell lymphomas with unclear significance. Here the authors show that they cooperate to skew B cell fate decisions and induce a CD8-depleted immune-evasive microenvironment to facilitate lymphomagenesis.

Jie Li
Christopher R. Chin
Ari M. Melnick
ResearchOpen Access03 Apr 2024
Nature Communications

Volume: 15, P: 1-22
Multimodal and spatially resolved profiling identifies distinct patterns of T cell infiltration in nodal B cell lymphoma entities

Roider, Baertsch et al. present a spatially resolved resource map of the T cell infiltration landscape across and within patients with distinct B cell non-Hodgkin lymphoma entities.

Tobias Roider
Marc A. Baertsch
Sascha Dietrich
ResearchOpen Access20 Feb 2024
Nature Cell Biology

Volume: 26, P: 478-489
PARP14 is a novel target in STAT6 mutant follicular lymphoma

Michael Mentz
William Keay
Oliver Weigert
ResearchOpen Access18 Jul 2022
Leukemia

Volume: 36, P: 2281-2292
ARID1A mutations protect follicular lymphoma from FAS-dependent immune surveillance by reducing RUNX3/ETS1-driven FAS-expression

Martina Antoniolli
Maria Solovey
Oliver Weigert
ResearchOpen Access23 Jan 2025
Cell Death & Differentiation

Volume: 32, P: 899-910
Identification of genetic subtypes in follicular lymphoma

Victoria Shelton
Rajesh Detroja
Robert Kridel
ResearchOpen Access07 Aug 2024
Blood Cancer Journal

Volume: 14, P: 1-13
Novel insights into the pathogenesis of follicular lymphoma by molecular profiling of localized and systemic disease forms

Sabrina Kalmbach
Michael Grau
Heike Horn
ResearchOpen Access10 Aug 2023
Leukemia

Volume: 37, P: 2058-2065