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Showing 1–3 of 3 results
Advanced filters: Author: Vicki L. Emms Clear advanced filters

  • Reactive carbonyl compounds pose toxicity challenges as pollutants and metabolites; however, synthetic scavengers for detoxification remain underdeveloped. Here, the authors demonstrate that 1-amino-but-3-enes, particularly those with phenyl groups, selectively scavenge formaldehyde and glyoxylic acid, offering potential for biomedical applications.

    • Natasha F. A. Bulman
    • Vicki L. Emms
    • Richard J. Hopkinson
    ResearchOpen Access
    Communications Chemistry
    P: 1-7

  • Chemically reactive metabolites such as formaldehyde are often toxic and are proposed to react promiscuously with biomolecules. New work shows that some reactive sites on proteins are uniquely sensitive to formaldehyde, leading to functionally important regulation of protein and cell functions.

    • Vicki L. Emms
    • Sara Y. Chothia
    • Richard J. Hopkinson
    News & Views
    Nature Chemical Biology
    Volume: 20, P: 268-270