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Showing 1–2 of 2 results
Advanced filters: Author: Victor Adebomi Clear advanced filters
  • A method for de novo design of peptide macrocyles called RFpeptides has been developed. RFpeptides is an extension of RoseTTAFold2 and RFdiffusion and combines structure prediction and protein backbone generation for rapid and custom design of macrocyclic peptide binders.

    • Stephen A. Rettie
    • David Juergens
    • Gaurav Bhardwaj
    ResearchOpen Access
    Nature Chemical Biology
    Volume: 21, P: 1948-1956
  • AfCycDesign: Cyclic offset to the relative positional encoding in AlphaFold2 enables accurate structure prediction, sequence redesign, and de novo hallucination of cyclic peptide monomers and binders.

    • Stephen A. Rettie
    • Katelyn V. Campbell
    • Gaurav Bhardwaj
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-15