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Showing 1–6 of 6 results
Advanced filters: Author: Victor Derkach Clear advanced filters

  • Plasticity at central glutamatergic synapses is central to learning and memory and involves alterations in the functional properties and trafficking of synaptic AMPA receptors. The authors provide insights into AMPA receptor regulation and subsequent changes in synaptic strength.

    • Victor A. Derkach
    • Michael C. Oh
    • Thomas R. Soderling
    Reviews
    Nature Reviews Neuroscience
    Volume: 8, P: 101-113

  • Neurons in the nucleus of the solitary tract (NTS) are known to receive visceral signals from the gut during feeding. Here, the authors identify two populations of CCK- and DBH-expressing NTS neurons that work to suppress food intake when activated via opto- or chemogenetic stimulation.

    • Carolyn W. Roman
    • Victor A. Derkach
    • Richard D. Palmiter
    ResearchOpen Access
    Nature Communications
    Volume: 7, P: 1-11

  • The authors show that oxytocin-receptor-expressing neurons in the parabrachial nucleus are key regulators of fluid homeostasis that suppress fluid intake when activated, but do not decrease food intake after fasting or salt intake after salt depletion.

    • Philip J. Ryan
    • Silvano I. Ross
    • Richard D. Palmiter
    ResearchOpen Access
    Nature Neuroscience
    Volume: 20, P: 1722-1733

  • Insights into the molecular mechanism of synaptic plasticity suggest that AMPA receptor phosphorylation by CaMKII accelerates channel opening and that TARPs preserve this regulation despite the presence of a GluA2 subunit.

    • Victor Derkach
    News & Views
    Nature Neuroscience
    Volume: 14, P: 674-675