Advanced search

Filter By:

Journal Check one or more journals to show results from those journals only.

Choose more journals

Article type Check one or more article types to show results from those article types only.
Subject Check one or more subjects to show results from those subjects only.
Date Choose a date option to show results from those dates only.

Custom date range

Clear all filters
Sort by:
Showing 1–4 of 4 results
Advanced filters: Author: Victor J. Cee Clear advanced filters

  • Chimeric antigen receptor (CAR) T cells specific for an antigen, BCMA, have shown efficacy in controlling multiple myeloma in some patients, but responses vary. Here the authors show that, by over-expressing a granzyme B-NOXA fusion protein in anti-BCMA CAR T cells, cancer cells are rendered more susceptible to apoptosis induction and CAR T-mediated killing.

    • Thomas Kimman
    • Marta Cuenca
    • Victor Peperzak
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-12

  • Treatment of KRASG12C-mutant cancer cells with the KRAS(G12C) inhibitor AMG 510 leads to durable response in mice, and anti-tumour activity in patients suggests that AMG 510 could be effective in patients for whom treatments are currently lacking.

    • Jude Canon
    • Karen Rex
    • J. Russell Lipford
    Research
    Nature
    Volume: 575, P: 217-223

  • Transposable element (TE) activity affects genome structure. Here, authors present GraffiTE, a framework for analysing polymorphic TEs in long reads or assemblies. It combines state-of-the-art variant search, TE annotation, and graph-genotyping, and has proven versatile across eukaryotic models.

    • Cristian Groza
    • Xun Chen
    • Clément Goubert
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-17