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Showing 1–11 of 11 results
Advanced filters: Author: Victoria E. Gibbon Clear advanced filters

  • The assembly of the genome of the koala provides insights into its adaptive biology and identifies gene expansions that contribute to its ability to detoxify eucalyptus-derived compounds and perceive plant secondary metabolites.

    • Rebecca N. Johnson
    • Denis O’Meally
    • Katherine Belov
    ResearchOpen Access
    Nature Genetics
    Volume: 50, P: 1102-1111

  • The mechanism by which relaxin activates the relaxin family peptide receptor-1 is poorly understood. Here, Sethi et al.identify a relaxin binding site in an extracellular linker between the LDLa and LRR domains and propose that relaxin binding stabilizes a helical conformation that leads to receptor activation.

    • Ashish Sethi
    • Shoni Bruell
    • Paul R. Gooley
    ResearchOpen Access
    Nature Communications
    Volume: 7, P: 1-12

  • The natural antisense transcript MAPT-AS1 interferes with translation of mRNA transcript into tau protein in the brain and may represent a general mechanism for controlling levels of intrinsically disordered proteins, with particular relevance for neurodegeneration.

    • Roberto Simone
    • Faiza Javad
    • Rohan de Silva
    Research
    Nature
    Volume: 594, P: 117-123

  • Oakhurst rockshelter in South Africa documents marked cultural change during the Holocene, but genome-wide data from ancient human individuals at the site now demonstrate a remarkable degree of genetic continuity over the last 9,000 years: the contemporary ‡Khomani San and Karretjiemense from South Africa still show direct signs of relatedness to the Oakhurst hunter-gatherers.

    • Joscha Gretzinger
    • Victoria E. Gibbon
    • Stephan Schiffels
    ResearchOpen Access
    Nature Ecology & Evolution
    Volume: 8, P: 2121-2134

  • The genus Quercus (oaks) has diversified into over 450 species which often play dominant roles in the ecosystems in which they occur. Here the authors present a genome and methylome for a California endemic oak, Quercus lobata, and describe features relevant to its evolutionary success.

    • Victoria L. Sork
    • Shawn J. Cokus
    • Steven L. Salzberg
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-15

  • In Africa, there is a disparity in ethics and permission requirements for molecular research on samples from living people versus ancient DNA. At the precipice of the archaeogenomics revolution, heritage agencies require updated policies and procedures for genetic and genomic research on African ancient DNA.

    • Victoria E. Gibbon
    Comments & Opinion
    Nature Reviews Genetics
    Volume: 21, P: 645-647

  • Hepatitis B virus (HBV) infection remains a global public health issue. This Review provides insights into the evolution of HBV and discusses the mechanisms by which HBV and hepatitis delta virus diversity occurs and the influence of this diversity on disease progression and treatment response.

    • Peter A. Revill
    • Thomas Tu
    • Margaret Littlejohn
    Reviews
    Nature Reviews Gastroenterology & Hepatology
    Volume: 17, P: 618-634

  • Embracing the underlying principles and processes of informed proxy consent or relational autonomy consent in human ancient DNA research can transform research.

    • Victoria E. Gibbon
    • Jessica C. Thompson
    • Sianne Alves
    Comments & OpinionOpen Access
    Communications Biology
    Volume: 7, P: 1-11